| 1280113-82-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1280113-82-7
• 化学式: C₁₂H₂₂O₃
• 分子量: 214.305
• InChiKey: VSLVTHXWPLDGBC-SRVKXCTJSA-N

反应信息

• 作为反应物：
  描述：

  、 对氯苯胺 在 indium(III) bromide 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以63%的产率得到4-(4-chlorophenylamino)-2-hexyl-5-methylcyclopent-2-enone
  参考文献：
  名称：

  InBr₃-Catalyzed Glycosidation of Glycals with Arylamines: An Alternative Approach To Access 4-Aminocyclopent-2-enones

  摘要：

  To turn side products into major products, a novel strategy to access biologically active 4-aminocyclopent-2-enones was developed. These compounds were originally identified as side products but became major products when 3,5-dimethylpyran-3,4-diol 7a was used as the substrate and 30% InBr3 as the catalyst. Aryl- or heteroarylamines as well as variously substituted glycals can be used in this reaction, and the corresponding 4-aminocyclopent-2-enones were obtained in moderate to good yields. These compounds can be further used to prepare 4-aminocarbocyclic nucleosides.

  DOI：

  10.1021/jo200243d