β-D-glucopyranosiduronate-(1→4)-2,5-anhydro-D-mannose | 1430336-34-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: β-D-glucopyranosiduronate-(1→4)-2,5-anhydro-D-mannose
• CAS: 1430336-34-7
• 化学式: C₁₂H₁₈O₁₁
• 分子量: 338.268
• InChiKey: CAKALQHRSRBTIN-UUGJNZGWSA-N

反应信息

• 作为反应物：
  描述：

  β-D-glucopyranosiduronate-(1→4)-2,5-anhydro-D-mannose 在 盐酸羟胺 、 sodium acetate 作用下， 以 水 为溶剂， 以55.556%的产率得到
  参考文献：
  名称：

  Preparation and application of a ‘clickable’ acceptor for enzymatic synthesis of heparin oligosaccharides

  摘要：

  A 'clickable' disaccharide was prepared by treating the aldehyde precursor with hydroxylamine, followed by the catalytic hydrogenation and diazotransfer reaction. This disaccharide was successfully applied to the elongation of the backbone construction of ultralow molecular weight (ULMW) heparins using two bacterial glycosyl transferases, N-acetyl glucosaminyl transferase from Escherichia coli K5 (KfiA) and heparosan synthase-2 (pmHS2) from Pasteurella multocida. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2013.02.010