durinskiol A

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: durinskiol A
• 英文别名: 7-[4-[4-(2,3-Dihydroxyhexadec-15-enyl)-2-hydroxy-13-methyl-5,7,9-trioxadispiro[5.1.58.26]pentadecan-10-yl]-1,3-dihydroxybutyl]-2-[2-[6-[4-[4,5-dihydroxy-6-[2-hydroxy-3-[4-hydroxy-6-[[5-hydroxy-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-6-(2,8,10-trihydroxy-6,12,15-trimethylpentacos-24-enyl)oxan-2-yl]methyl]-2-methyl-3-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl]propyl]-6-methyloxan-2-yl]-2-hydroxybutyl]-3,4-dihydroxyoxan-2-yl]-2-hydroxyethyl]oxepane-3,4,5-triol；7-[4-[4-(2,3-dihydroxyhexadec-15-enyl)-2-hydroxy-13-methyl-5,7,9-trioxadispiro[5.1.58.26]pentadecan-10-yl]-1,3-dihydroxybutyl]-2-[2-[6-[4-[4,5-dihydroxy-6-[2-hydroxy-3-[4-hydroxy-6-[[5-hydroxy-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-6-(2,8,10-trihydroxy-6,12,15-trimethylpentacos-24-enyl)oxan-2-yl]methyl]-2-methyl-3-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl]propyl]-6-methyloxan-2-yl]-2-hydroxybutyl]-3,4-dihydroxyoxan-2-yl]-2-hydroxyethyl]oxepane-3,4,5-triol
• 化学式: C₁₁₀H₁₉₈O₃₈
• 分子量: 2128.76
• InChiKey: QWPYDAUIDUQDNC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  148
• 可旋转键数：
  62
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  637
• 氢给体数：
  26
• 氢受体数：
  38

反应信息

• 作为反应物：
  描述：

  durinskiol A 在 臭氧 、 二甲基硫 作用下， 以 甲醇 为溶剂， 反应 6.02h， 生成
  参考文献：
  名称：

  Durinskiol A: a long carbon-chain polyol compound from the symbiotic dinoflagellate Durinskia sp.

  摘要：

  A long carbon-chain polyol compound with a molecular weight of 2128 mu, durinskiol A (1) was isolated from the cultured symbiotic dinoflagellate Durinskia sp. Its planar structure was elucidated based on 2D-NMR and MS/MS analysis. Durinskiol A (1) caused a short body length, abnormal pigment pattern, and pericardiac and yolk-sac edema in zebrafish. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.046

文献信息

• Durinskiol A: a long carbon-chain polyol compound from the symbiotic dinoflagellate Durinskia sp.
  作者：Masaki Kita、Michael C. Roy、Eric R.O. Siwu、Isao Noma、Takahiro Takiguchi、Motoyuki Itoh、Kaoru Yamada、Tomoyuki Koyama、Takeshi Iwashita、Daisuke Uemura

  DOI：10.1016/j.tetlet.2007.03.046

  日期：2007.5

  A long carbon-chain polyol compound with a molecular weight of 2128 mu, durinskiol A (1) was isolated from the cultured symbiotic dinoflagellate Durinskia sp. Its planar structure was elucidated based on 2D-NMR and MS/MS analysis. Durinskiol A (1) caused a short body length, abnormal pigment pattern, and pericardiac and yolk-sac edema in zebrafish. (c) 2007 Elsevier Ltd. All rights reserved.