methyl 2-iodo-3-(5-imidazolyl)propanoate | 548437-05-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: methyl 2-iodo-3-(5-imidazolyl)propanoate
• 英文别名: methyl 3-(1H-imidazol-5-yl)-2-iodopropanoate
• CAS: 548437-05-4
• 化学式: C₇H₉IN₂O₂
• 分子量: 280.065
• InChiKey: FOJIQQIIMRMOTH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  55
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-Brom-3-(5-imidazolyl)-propionsaeure-methylester 在 sodium iodide 作用下， 以 水 、 丙酮 为溶剂， 生成 methyl 2-iodo-3-(5-imidazolyl)propanoate
  参考文献：
  名称：

  US2003/118636

  摘要：

  公开号：

文献信息

• Delivery of a substance to a pre-determined site
  申请人：Friesen Heinz Edward Robert

  公开号：US20050272677A1

  公开（公告）日：2005-12-08

  The invention is directed to delivery vehicles for delivering a substance of interest to a predetermined site. The delivery vehicle includes a substance and means for inducing availability of at least one compartment of the delivery vehicle toward the exterior, thus, allowing access of the substance to the exterior of the delivery vehicle at the predetermined site. The invention is further directed to uses of the delivery vehicle and methods for preparing the delivery vehicle.

  本发明涉及用于将所需物质传递至预定地点的传递车辆。该传递车辆包括物质和诱导至少一个传递车辆隔室向外部可用的手段，从而允许在预定地点将物质访问到传递车辆的外部。本发明还涉及传递车辆的用途和制备传递车辆的方法。
• Delivery of small hydrophilic molecules packaged into lipid vesicles
  申请人：——

  公开号：US20030118636A1

  公开（公告）日：2003-06-26

  Methods and compositions for the generation of vehicles for delivering small molecules are disclosed. In one aspect, lipid vesicles having a proteinaceous channel and small molecules are generated. The proteinaceous channel and/or the lipid vesicle are formulated such that the small molecule is released in the vicinity of or near a target cell. The target cell may be located in vitro or in vivo.

  本发明揭示了用于生成用于传递小分子的载体的方法和组合物。在一个方面，生成具有蛋白质通道和小分子的脂质囊泡。蛋白质通道和/或脂质囊泡的配方使小分子在靠近或接近目标细胞的位置释放。目标细胞可以位于体外或体内。
• DELIVERY OF SMALL HYDROPHILIC MOLECULES PACKAGED INTO LIPID VESICLES
  申请人：Applied NanoSystems B.V.

  公开号：EP1397123B1

  公开（公告）日：2009-12-30
• DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE
  申请人：Applied NanoSystems B.V.

  公开号：EP1490028A1

  公开（公告）日：2004-12-29
• [EN] DELIVERY OF SMALL HYDROPHILIC MOLECULES PACKAGED INTO LIPID VESICLES<br/>[FR] LIBERATION DE PETITES MOLECULES HYDROPHILES COMPRISES DANS DES VESICULES LIPIDIQUES
  申请人：APPLIED NANOSYSTEMS BV

  公开号：WO2003000233A2

  公开（公告）日：2003-01-03

  Means and methods are provided for the generation and use of delivery vehicles for small molecules. In one aspect of the invention lipid vesicles comprising proteinaceous channel and said small molecules are generated. Said proteinaceous channel and/or said lipid vesicle are formulated such that said small molecule is released in the vicinity of a target cell. Said target cell may be present in vitro or in vivo.