5-isopropyl-3,3-dimethyldihydrofuran-2(3H)-one | 22092-71-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 5-isopropyl-3,3-dimethyldihydrofuran-2(3H)-one
• 英文别名: 5-isopropyl-3,3-dimethyl-dihydro-furan-2-one；5-Isopropyl-3,3-dimethyl-dihydro-furan-2-on；3,3-Dimethyl-5-propan-2-yloxolan-2-one；3,3-dimethyl-5-propan-2-yloxolan-2-one
• CAS: 22092-71-3
• 化学式: C₉H₁₆O₂
• 分子量: 156.225
• InChiKey: CNKDRQATIPRLDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-羟基-2,2,5-三甲基-己酸 在 氢碘酸 作用下， 生成 5-isopropyl-3,3-dimethyldihydrofuran-2(3H)-one
  参考文献：
  名称：

  Kukulesko, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1896, vol. 28, p. 297

  摘要：

  DOI：

文献信息

• Formation of Quaternary Carbon Centers by Highly Regioselective Hydroformylation with Catalytic Amounts of a Reversibly Bound Directing Group
  作者：Yusuke Ueki、Hideto Ito、Ippei Usui、Bernhard Breit

  DOI：10.1002/chem.201101186

  日期：2011.7.25

  Directly opposing Keulemans rule! Phosphinites work as reversibly bound directing groups allowing for the first highly regioselective hydroformylation of 3‐substituted homoallylic alcohols to construct quaternary carbon centers. This method enables the atom‐economical synthesis of a wide range of α,α‐disubstituted γ‐lactones and highly substituted tetrahydrofurans (see scheme; R1, R2=alkyl/aryl).

  直接反对Keulemans统治！次膦酸盐作为可逆结合的导向基团起作用，从而允许3-取代均烯丙基醇的首次高度区域选择性加氢甲酰化以构建季碳中心。该方法可实现多种α，α-二取代的γ-内酯和高度取代的四氢呋喃的原子经济合成（参见方案； R 1，R 2 =烷基/芳基）。
• POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL POLYMERIZED FILMS
  申请人：JNC CORPORATION

  公开号：US20180119014A1

  公开（公告）日：2018-05-03

  To provide a polymerizable liquid crystal compound in order to produce a retardation film having excellent front contrast. A polymerizable liquid crystal composition including a compound represented by Formula (1). In Formula (1), for example, W 1 is an alkoxycarbonyl group having 1 to 10 carbon atoms, an alkanoyl group having 1 to 10 carbon atoms, or a polymerizable functional group, A 1 is independently 1,4-phenylene or naphthalene-2,6-diyl, Z 1 is a linking group, m and n are independently an integer of 0 to 7, and satisfy 3≤m+n≤8, and P 1 is a polymerizable functional group.

  为了生产具有优异前对比度的减速膜，提供一种可聚合液晶化合物。包括由式（1）表示的化合物的可聚合液晶组合物。在式（1）中，例如，W1是具有1至10个碳原子的烷氧羰基、具有1至10个碳原子的烷酰基或可聚合官能团，A1独立地为1,4-苯撑或萘-2,6-二基，Z1为连接基，m和n独立地为0至7的整数，并满足3≤m+n≤8，P1为可聚合官能团。
• Polymerizable liquid crystal compound, polymerizable liquid crystal composition and liquid crystal polymerized film
  申请人：JNC CORPORATION

  公开号：US10844283B2

  公开（公告）日：2020-11-24

  A polymerizable liquid crystal compound represented by formula (1). In formula (1), A1 is 1,4-phenylene, 1,4-cyclohexylene, 1,4-cyclohexenylene, pyridine-2,5-diyl, 1,3-dioxane-2,5-diyl or naphthalene-2,6-diyl, Z1 is a connecting group, m and n are independently an integer from 0 to 5, in which an expression: 1≤m+n≤8 holds, X1 is alkylene having 1 to 5 carbons, in which an atom thereof may be replaced by a hetero atom, and at least one of R1 is a polymerizable functional group.

  一种由式（1）表示的可聚合液晶化合物。在式 (1) 中，A1 是 1,4-亚苯基、1,4-环己烯、1,4-环己烯、吡啶-2,5-二基、1,3-二噁烷-2,5-二基或萘-2,6-二基，Z1 是连接基团，m 和 n 独立地为 0 至 5 的整数，其中表达式：1≤m+n≤8 成立，X1 是具有 1 至 5 个碳原子的亚烷基，其中一个原子可被杂原子取代，R1 中至少有一个是可聚合的官能团。
• Coucoulesco, Buletinul Societăţii de Chimie din România, vol. 5, p. 68
  作者：Coucoulesco

  DOI：——

  日期：——
• Kukulesko, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1896, vol. 28, p. 297
  作者：Kukulesko

  DOI：——

  日期：——