1-[2-methyl-5-(N-(3,6,9,12-tetraoxadodecan-1-ol-4-yl)thien-3-yl)]-2-[2-methyl-5-(4-(hexadecyloxy)benzene-4-yl)thien-3-yl]cyclopentene | 1084905-42-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-[2-methyl-5-(N-(3,6,9,12-tetraoxadodecan-1-ol-4-yl)thien-3-yl)]-2-[2-methyl-5-(4-(hexadecyloxy)benzene-4-yl)thien-3-yl]cyclopentene
• 英文别名: 2-[2-[2-[2-[4-[4-[2-[5-(4-Hexadecoxyphenyl)-2-methylthiophen-3-yl]cyclopenten-1-yl]-5-methylthiophen-2-yl]pyridin-1-ium-1-yl]ethoxy]ethoxy]ethoxy]ethanol;bromide
• CAS: 1084905-42-9
• 化学式: Br*C₅₀H₇₂NO₅S₂
• 分子量: 911.161
• InChiKey: RWYORSYXYFMXDH-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  10.05
• 重原子数：
  59
• 可旋转键数：
  31
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  118
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1-[2-methyl-5-(N-(3,6,9,12-tetraoxadodecan-1-ol-4-yl)thien-3-yl)]-2-[2-methyl-5-(4-(hexadecyloxy)benzene-4-yl)thien-3-yl]cyclopentene 生成
  参考文献：
  名称：

  Amphiphilic Diarylethene as a Photoswitchable Probe for Imaging Living Cells

  摘要：

  This communication reports a unique example of water-soluble and fluorescent-switchable amphiphilic diarylethene. This compound performs stable vesicle aggregation in water and shows aggregation-dependent emission in its open form. The fluorescence can be effectively switched by alternating between UV and visible light irradiation. This compound thus can stain KB cells for switchable living cell imaging with excellent resistance to fatigue.

  DOI：

  10.1021/ja8043163
• 作为产物：
  描述：

  12-bromo-3,6,9,12-tetraoxadodecan-1-ol 、 1-[2-methyl-5-(pyridine-4-yl)thien-3-yl]-2-[2-methyl-5-(4-(hexadecyloxy)benzene-4-yl)thien-3-yl]cyclopentene 以 乙腈 为溶剂， 反应 24.0h， 以20%的产率得到1-[2-methyl-5-(N-(3,6,9,12-tetraoxadodecan-1-ol-4-yl)thien-3-yl)]-2-[2-methyl-5-(4-(hexadecyloxy)benzene-4-yl)thien-3-yl]cyclopentene
  参考文献：
  名称：

  Amphiphilic Diarylethene as a Photoswitchable Probe for Imaging Living Cells

  摘要：

  This communication reports a unique example of water-soluble and fluorescent-switchable amphiphilic diarylethene. This compound performs stable vesicle aggregation in water and shows aggregation-dependent emission in its open form. The fluorescence can be effectively switched by alternating between UV and visible light irradiation. This compound thus can stain KB cells for switchable living cell imaging with excellent resistance to fatigue.

  DOI：

  10.1021/ja8043163

文献信息

• Amphiphilic Diarylethene as a Photoswitchable Probe for Imaging Living Cells
  作者：Ying Zou、Tao Yi、Shuzhang Xiao、Fuyou Li、Chunyan Li、Xia Gao、Junchen Wu、Mengxiao Yu、Chunhui Huang

  DOI：10.1021/ja8043163

  日期：2008.11.26

  This communication reports a unique example of water-soluble and fluorescent-switchable amphiphilic diarylethene. This compound performs stable vesicle aggregation in water and shows aggregation-dependent emission in its open form. The fluorescence can be effectively switched by alternating between UV and visible light irradiation. This compound thus can stain KB cells for switchable living cell imaging with excellent resistance to fatigue.