Diethyl 2-(2-methyl-5-oxohexan-3-yl)propanedioate | 1280737-42-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Diethyl 2-(2-methyl-5-oxohexan-3-yl)propanedioate
• CAS: 1280737-42-9
• 化学式: C₁₄H₂₄O₅
• 分子量: 272.342
• InChiKey: XGTIANNWWQWDAD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  69.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  Diethyl 2-(2-methyl-5-oxohexan-3-yl)propanedioate 在 水 、 potassium hydroxide 作用下， 生成
  参考文献：
  名称：

  Total synthesis of (±)-hibiscone C

  摘要：

  A total synthesis of (+/-)-hibiscone C, one member of the furanosteroid family of natural products that also includes viridin and wortmannin, is reported. Two new pathways for formation of the key diacyl furan subunit are described. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.01.111
• 作为产物：
  描述：

  5-甲基-3-己烯-2-酮 、 丙二酸二乙酯 在 sodium ethanolate 作用下， 以 乙醇 为溶剂， 生成 Diethyl 2-(2-methyl-5-oxohexan-3-yl)propanedioate
  参考文献：
  名称：

  Total synthesis of (±)-hibiscone C

  摘要：

  A total synthesis of (+/-)-hibiscone C, one member of the furanosteroid family of natural products that also includes viridin and wortmannin, is reported. Two new pathways for formation of the key diacyl furan subunit are described. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.01.111

文献信息

• Total synthesis of (±)-hibiscone C
  作者：Sinziana Ungureanu、Maggie Meadows、Joel Smith、David B. Duff、James M. Burgess、Brian C. Goess

  DOI：10.1016/j.tetlet.2011.01.111

  日期：2011.3

  A total synthesis of (+/-)-hibiscone C, one member of the furanosteroid family of natural products that also includes viridin and wortmannin, is reported. Two new pathways for formation of the key diacyl furan subunit are described. (C) 2011 Elsevier Ltd. All rights reserved.