N,N'-diethyl-[2,2'-bipyridine]-6,6'-diamine | 1346267-97-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N,N'-diethyl-[2,2'-bipyridine]-6,6'-diamine
• 英文别名: N6,N6'-diethyl[2,2'-bipyridinyl]-6,6'-diamine；N-ethyl-6-[6-(ethylamino)pyridin-2-yl]pyridin-2-amine
• CAS: 1346267-97-7
• 化学式: C₁₄H₁₈N₄
• 分子量: 242.324
• InChiKey: LWYYUCYZHSIWMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  49.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂ 、 N,N'-diethyl-[2,2'-bipyridine]-6,6'-diamine 以 not given 为溶剂， 生成 [Ru(1,2-bis(2,2'-bipyridyl-6-yl)ethyne)(p-cumene)(chloride)]⁽¹⁺⁾
  参考文献：
  名称：

  Photocatalytic Splitting of CS₂ to S₈ and a Carbon–Sulfur Polymer Catalyzed by a Bimetallic Ruthenium(II) Compound with a Tertiary Amine Binding Site: Toward Photocatalytic Splitting of CO₂?

  摘要：

  The catalytic photocleavage of CS2 to S-8 and a (CxSy)(n) polymer with visible light using a dinuclear ruthenium(II) compound with a bipyridine units for photoactivity and a vicinal tertiary amine binding site for CS2 activation was studied. The catalyst was characterized by X-ray diffraction, H-1 NMR, and C-13 NMR, ESI-MS and elemental analysis. CS2 photocleavage was significant (240 turnovers, 20 h) to yield isolable S-8 and a (CxSy)(n) polymer. A mononuclear catalyst or one without an amine binding site showed significantly less activity. XPS of the (CxSy)(n) polymer showed a carbon/sulfur ratio similar to 1.5-1.6 indicating that in part both C-S bonds of CS2 had been cleaved. Catalyst was also included within the polymer. The absence of peaks in the H-1 NMR verified the (CxSy)(n) nature of the polymer, while C-13 NMR and IR indicated that the polymer had multiple types of C-S and C-C bonds.

  DOI：

  10.1021/ic2008045
• 作为产物：
  描述：

  2,2'-二吡啶-6,6'-二胺 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 36.0h， 生成 N,N'-diethyl-[2,2'-bipyridine]-6,6'-diamine
  参考文献：
  名称：

  苯酚的合成：芳基卤化物与水的有机光氧化还原/镍双催化羟化反应

  摘要：

  报道了在协同的有机光氧化还原和镍催化下，芳基卤化物与水的高效羟基化反应。在配体上的分子内碱基促进去质子化之后，所得酚的OH基团起源于水。重要的是，芳基溴化物和反应性较低的芳基氯用作有效的底物，以提供具有广泛官能团的酚。不需要强大的无机碱或昂贵的贵金属催化剂，该方法可用于有效制备各种酚，并使多官能药学上相关的芳基卤化物羟基化。

  DOI：

  10.1002/anie.201710698

文献信息

• Synthesis of Phenols: Organophotoredox/Nickel Dual Catalytic Hydroxylation of Aryl Halides with Water
  作者：Liu Yang、Zhiyan Huang、Gang Li、Wei Zhang、Rui Cao、Chao Wang、Jianliang Xiao、Dong Xue

  DOI：10.1002/anie.201710698

  日期：2018.2.12

  A highly effective hydroxylation reaction of aryl halides with water under synergistic organophotoredox and nickel catalysis is reported. The OH group of the resulting phenols originates from water, following deprotonation facilitated by an intramolecular base group on the ligand. Significantly, aryl bromides as well as less reactive aryl chlorides served as effective substrates to afford phenols with

  报道了在协同的有机光氧化还原和镍催化下，芳基卤化物与水的高效羟基化反应。在配体上的分子内碱基促进去质子化之后，所得酚的OH基团起源于水。重要的是，芳基溴化物和反应性较低的芳基氯用作有效的底物，以提供具有广泛官能团的酚。不需要强大的无机碱或昂贵的贵金属催化剂，该方法可用于有效制备各种酚，并使多官能药学上相关的芳基卤化物羟基化。
• Photocatalytic Splitting of CS₂ to S₈ and a Carbon–Sulfur Polymer Catalyzed by a Bimetallic Ruthenium(II) Compound with a Tertiary Amine Binding Site: Toward Photocatalytic Splitting of CO₂?
  作者：Konstantin Livanov、Vedichi Madhu、Ekambaram Balaraman、Linda J. W. Shimon、Yael Diskin-Posner、Ronny Neumann

  DOI：10.1021/ic2008045

  日期：2011.11.21

  The catalytic photocleavage of CS2 to S-8 and a (CxSy)(n) polymer with visible light using a dinuclear ruthenium(II) compound with a bipyridine units for photoactivity and a vicinal tertiary amine binding site for CS2 activation was studied. The catalyst was characterized by X-ray diffraction, H-1 NMR, and C-13 NMR, ESI-MS and elemental analysis. CS2 photocleavage was significant (240 turnovers, 20 h) to yield isolable S-8 and a (CxSy)(n) polymer. A mononuclear catalyst or one without an amine binding site showed significantly less activity. XPS of the (CxSy)(n) polymer showed a carbon/sulfur ratio similar to 1.5-1.6 indicating that in part both C-S bonds of CS2 had been cleaved. Catalyst was also included within the polymer. The absence of peaks in the H-1 NMR verified the (CxSy)(n) nature of the polymer, while C-13 NMR and IR indicated that the polymer had multiple types of C-S and C-C bonds.