4,4′-[（8,16-二氢-8,16-二氧二苯并[a，j]苝-2,10-二基）二氧基]二丁酸二（N-琥珀酰亚胺酯） | 243670-15-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 中文名称: 4,4′-[（8,16-二氢-8,16-二氧二苯并[a，j]苝-2,10-二基）二氧基]二丁酸二（N-琥珀酰亚胺酯）
• 英文名称: di-N-succinimidyl 4,4'-[2,10-(8,16-dihydro-8,16-dioxodibenzo[a,j]perylene)bis(oxy)]bisbutanoate
• 英文别名: 4,4'-[(8,16-Dihydro-8,16-dioxodibenzo[a,j]perylene-2,10-diyl)dioxy]dibutyric acid di(N-succinimidyl ester)；(2,5-dioxopyrrolidin-1-yl) 4-[[19-[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutoxy]-9,22-dioxo-6-heptacyclo[13.11.1.12,10.03,8.016,21.023,27.014,28]octacosa-1,3(8),4,6,10,12,14(28),15(27),16(21),17,19,23,25-tridecaenyl]oxy]butanoate
• CAS: 243670-15-7
• 化学式: C₄₄H₃₂N₂O₁₂
• 分子量: 780.744
• InChiKey: CDBVPXLQWBQDPN-UHFFFAOYSA-N

物化性质

• 熔点：
  188-192 °C
• 密度：
  1.56±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  58
• 可旋转键数：
  14
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  180
• 氢给体数：
  0
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  N-羟基丁二酰亚胺 、 4,4′-[（8,16-二氢-8,16-二氧二苯并[a，j]苝-2,10-二基）二氧基]二丁酸 在 N,N'-二环己基碳二亚胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 20.0h， 以75%的产率得到4,4′-[（8,16-二氢-8,16-二氧二苯并[a，j]苝-2,10-二基）二氧基]二丁酸二（N-琥珀酰亚胺酯）
  参考文献：
  名称：

  Far-Red Dibenzo[a,j]Perylene-8,16-Dione Dyes as Fluorescent Enzyme Substrates and Tags for Biomolecules

  摘要：

  The synthesis of fluorescent 2,10-derivatives of the title chromophore are described. The substituents contain amino-reactive N-hydroxysuccinimde eater and thiol-reactive iodoacetamide groups for attachment to biomolecules. A phosphate derivative was also prepared as an enzyme substrate.

  DOI：

  10.1080/00397910008087092

文献信息

• ELECTROCHEMICAL SENSORS AND METHODS FOR USING ELECTROCHEMICAL SENSORS TO DETECT PLANT PATHOGEN INFECTION
  申请人：University of Georgia Research Foundation, Inc.

  公开号：US20200115730A1

  公开（公告）日：2020-04-16

  Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds.
• US8642308B1
  申请人：——

  公开号：US8642308B1

  公开（公告）日：2014-02-04
• US8871483B1
  申请人：——

  公开号：US8871483B1

  公开（公告）日：2014-10-28
• [EN] ELECTROCHEMICAL SENSORS AND METHODS FOR USING ELECTROCHEMICAL SENSORS TO DETECT PLANT PATHOGEN INFECTION<br/>[FR] CAPTEURS ÉLECTROCHIMIQUES ET PROCÉDÉS D'UTILISATION DE CAPTEURS ÉLECTROCHIMIQUES POUR DÉTECTER UNE INFECTION PAR UN AGENT PHYTOPATHOGÈNE
  申请人：UNIV GEORGIA

  公开号：WO2016168585A1

  公开（公告）日：2016-10-20

  Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds.
• Far-Red Dibenzo[<i>a,j</i>]Perylene-8,16-Dione Dyes as Fluorescent Enzyme Substrates and Tags for Biomolecules
  作者：Leslie W. Deady、Andrew B. Hughes、Indumathy B. Mahadevan、Nurul H. Quazi、Leann M. Tilley

  DOI：10.1080/00397910008087092

  日期：2000.3

  The synthesis of fluorescent 2,10-derivatives of the title chromophore are described. The substituents contain amino-reactive N-hydroxysuccinimde eater and thiol-reactive iodoacetamide groups for attachment to biomolecules. A phosphate derivative was also prepared as an enzyme substrate.