GlcA(b1-3)GalNAc(b1-4)GlcA(b1-3)Gal(b1-3)Gal(b1-4)b-Xyl

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: GlcA(b1-3)GalNAc(b1-4)GlcA(b1-3)Gal(b1-3)Gal(b1-4)b-Xyl
• 英文别名: (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5R,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-2-carboxy-6-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-[(3R,4R,5R,6R)-4,5,6-trihydroxyoxan-3-yl]oxyoxan-4-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
• 化学式: C₃₇H₅₉NO₃₂
• 分子量: 1029.86
• InChiKey: YPFDLUIPQHGQFF-VPXYFUCSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -10.6
• 重原子数：
  70
• 可旋转键数：
  16
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  529
• 氢给体数：
  19
• 氢受体数：
  32

反应信息

• 作为产物：
  描述：

  生成 GlcA(b1-3)GalNAc(b1-4)GlcA(b1-3)Gal(b1-3)Gal(b1-4)b-Xyl
  参考文献：
  名称：

  Synthesis of sulfated glycohexaose of linkage region of chondroitin 4-sulfate: β-D-GlcA-(1→3){(SO3Na→4)}-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3 )-β-D-Gal-(1→4)-D-Xyl

  摘要：

  Stereocontrolled synthesis of glycohexaoses 3 and 4 which corresponds to the linkage region of chondroitin 4-sulfate to a core protein was achieved for the first time by employing glycotriosyl donor 5 and glycotriosyl acceptor 6.

  DOI：

  10.1016/s0040-4039(00)61790-2

文献信息

• Synthesis of sulfated glycohexaose of linkage region of chondroitin 4-sulfate: β-D-GlcA-(1→3){(SO3Na→4)}-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3 )-β-D-Gal-(1→4)-D-Xyl
  作者：Fumitaka Goto、Tomoya Ogawa

  DOI：10.1016/s0040-4039(00)61790-2

  日期：1992.11

  Stereocontrolled synthesis of glycohexaoses 3 and 4 which corresponds to the linkage region of chondroitin 4-sulfate to a core protein was achieved for the first time by employing glycotriosyl donor 5 and glycotriosyl acceptor 6.