6-methylapigenin | 5526-57-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 6-methylapigenin
• 英文别名: 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methylchromen-4-one
• CAS: 5526-57-8
• 化学式: C₁₆H₁₂O₅
• 分子量: 284.268
• InChiKey: ZLGRXDWWYMFIGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  8-去甲基桉树素 生成 6-methylapigenin
  参考文献：
  名称：

  Spectral characteristics of C-methylflavones

  摘要：

  DOI：

  10.1007/bf00575747

文献信息

• Vaporized medicants and methods of use
  申请人：Chong Corporation

  公开号：US10098918B2

  公开（公告）日：2018-10-16

  A method and formulation for delivering a sexual aid, such as epimedium or yohimbe, in a vaporized state using low temperatures to vaporize the formulation. The formulation contains an inert non-reactive compound that lowers the heat of vaporization of the formulation, and the active compound. The formulation may optionally contain glycerin, alcohol, and/or water. Examples of inert non-reactive compounds that can sufficiently lower the heat of vaporization of the formulation include propylene glycol, vegetable glycerin and polysorbate. The formulation can be vaporized using a hand-held low temperature vaporizer or atomizer.

  一种利用低温使制剂汽化的方法和制剂，以汽化状态提供性药物，如淫羊藿或育亨宾。制剂中含有一种惰性非反应性化合物，可降低制剂和活性化合物的汽化热。制剂可选择含有甘油、酒精和/或水。能充分降低制剂汽化热的惰性非反应性化合物包括丙二醇、植物甘油和聚山梨醇酯。可以使用手持式低温汽化器或雾化器对配方进行汽化。
• SEDATIVE MATERIALS AND TREATMENTS
  申请人：UNIVERSITY OF STRATHCLYDE

  公开号：EP1503771A1

  公开（公告）日：2005-02-09
• Antioxidant of Bamboo Leaves and Its Uses
  申请人：Zhang Ying

  公开号：US20080233242A1

  公开（公告）日：2008-09-25

  The present invention discloses the composition of antioxidant of bamboo leaves (AOB) and its use. The purpose of present invention is to provide a new food additive which is natural, nutritional, and muti-functional, and which is of rich resources, safety, good effect, and low cost. AOB is yellow or brown powders or particles obtained from bamboo leaves, wherein the main antioxidative components include flavones, lactones, phenolic acids. AOB can either inhibit lipid autoxidation chain reaction, or chelate transitional metal ions, and can be used as primary and second antioxidant. AOB can eliminate nitrite and inhibit the synthesis of N-nitrosamine, and has anti-bacteria, bacteriostatic, deodorizing, aroma enhancing etc. functions. AOB can be commonly used in oil-containing food, meat product, fishery product, expanded food etc. food systems.
• Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B)
  申请人：Oliver Yoa-Pu Hu

  公开号：US20090074708A1

  公开（公告）日：2009-03-19

  A UGT2B inhibitor capable of increasing the bio-availability of a drug, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin, β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, puerarin, trans-cinnamaldehyde, 3-phenylpropyl acetate, isoliquritigenin, paeoniflorin, gallic acid, genistein, glycyrrhizin, protocatechuic acid, ethyl myristate, umbelliferone, PEG (Polyethylene glycol) 400, PEG 2000, PEG 4000, Tween 20, Tween 60, Tween 80, BRIJ® 58, BRIJ® 76, Pluronic® F68, Pluronic® F127, and a combination thereof. A UGT2B enhancer capable of enhancing a clearance rate of morphine-like analgesic agents, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: nordihydroguaiaretic acid, wogonin, trans-cinnamic acid, baicalein, quercetin, daidzein, oleanolic acid, homoorientin, hesperetin, narigin, neohesperidin, (+)-epicatechin, hesperidin, liquiritin, eriodictyol, formononetin, quercitrin, genkwanin, kaempferol, isoquercitrin, (+)-catechin, naringenin, daidzin, (−)-epicatechin, luteolin-7-glucoside, ergosterol, rutin, luteolin, ethyl myristate, apigenin, 3-phenylpropyl acetate, umbelliferone, glycyrrhizin, protocatechuic acid, poncirin, isovitexin, 6-gingerol, cineole, genistein, trans-cinnamaldehyde, and a combination thereof.
• USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS
  申请人：CHIOU Lih-Chu

  公开号：US20120029066A1

  公开（公告）日：2012-02-02

  Novel Use of flavones having 2-phenylchromen-4-one skeleton is disclosed herein. The flavones are useful as lead compounds for manufacturing a medicament or a pharmaceutical composition for treating a patient diagnosed with a psychiatric disorder with sensorimotor gating deficits.