5-phenoxy-2,3-dihydro-1H-indene | 1353547-69-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-phenoxy-2,3-dihydro-1H-indene
• CAS: 1353547-69-9
• 化学式: C₁₅H₁₄O
• 分子量: 210.276
• InChiKey: ABBXLIATSQBDNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  碘苯 、 5-茚醇 在 copper(I) oxide 、 caesium carbonate 、 1H-咪唑-4-甲酸 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以96%的产率得到5-phenoxy-2,3-dihydro-1H-indene
  参考文献：
  名称：

  Highly efficient copper catalytic system for the O-arylation of phenol with iodoarene

  摘要：

  An efficient Cu-catalyzed O-arylation was carried out by involving phenols with iodoarenes to afford various substituted diarylether derivatives with tiny loading of Cu2O and 1H-imidazole-4-carboxylic acid as catalytic system under mild conditions, which provided good to excellent yields with good tolerance of functional groups. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.10.149

文献信息

• COMPOSITIONS AND METHODS FOR INHIBITING RETICULON 4
  申请人：THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US20200062696A1

  公开（公告）日：2020-02-27

  Disclosed herein, inter alia, are compositions and methods useful for inhibiting reticulon 4 (RTN4).
• Highly efficient copper catalytic system for the O-arylation of phenol with iodoarene
  作者：An-Yi Cheng、Jen-Chieh Hsieh

  DOI：10.1016/j.tetlet.2011.10.149

  日期：2012.1

  An efficient Cu-catalyzed O-arylation was carried out by involving phenols with iodoarenes to afford various substituted diarylether derivatives with tiny loading of Cu2O and 1H-imidazole-4-carboxylic acid as catalytic system under mild conditions, which provided good to excellent yields with good tolerance of functional groups. (C) 2011 Elsevier Ltd. All rights reserved.