4-Oxo-4-[(1-phenylethyl)amino]but-2-enoic acid | 108088-06-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-Oxo-4-[(1-phenylethyl)amino]but-2-enoic acid
• 英文别名: 4-oxo-4-(1-phenylethylamino)but-2-enoic acid
• CAS: 108088-06-8
• 化学式: C₁₂H₁₃NO₃
• 分子量: 219.24
• InChiKey: YBCNEBVTRKGSFM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-Oxo-4-[(1-phenylethyl)amino]but-2-enoic acid 在 sodium acetate 、 乙酸酐 作用下， 以1.13 g的产率得到N-(S)-(-)-α-Methylbenzylmaleimide
  参考文献：
  名称：

  Tailor‐Made Pd _n L _{2 n} Metal‐Organic Cages through Covalent Post‐Synthetic Modification

  摘要：

  AbstractPost‐synthetic modification (PSM) is an effective approach for the tailored functionalization of metal‐organic architectures, but its generalizability remains challenging. Herein we report a general covalent PSM strategy to functionalize PdnL2n metal‐organic cages (MOCs, n=2, 12) through an efficient Diels–Alder cycloaddition between peripheral anthracene substituents and various functional motifs bearing a maleimide group. As expected, the solubility of functionalized Pd12L24 in common solvents can be greatly improved. Interestingly, concentration‐dependent circular dichroism and aggregation‐induced emission are achieved with chiral binaphthol (BINOL)‐ and tetraphenylethylene‐modified Pd12L24, respectively. Furthermore, Pd12L24 can be introduced with two different functional groups (e.g., chiral BINOL and achiral pyrene) through a step‐by‐step PSM route to obtain chirality‐induced circularly polarized luminescence. Moreover, similar results are readily observed with a smaller Pd2L4 system.

  DOI：

  10.1002/anie.202216977
• 作为产物：
  描述：

  马来酸酐 、 α-苯乙胺 以 二氯甲烷 为溶剂， 生成 4-Oxo-4-[(1-phenylethyl)amino]but-2-enoic acid
  参考文献：
  名称：

  Deshpande, Sunita R.; Maybhate, Shailaja P.; Likhite, Anjali P., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010, vol. 49, # 4, p. 487 - 488

  摘要：

  DOI：

文献信息

• Deshpande, Sunita R.; Maybhate, Shailaja P.; Likhite, Anjali P., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010, vol. 49, # 4, p. 487 - 488
  作者：Deshpande, Sunita R.、Maybhate, Shailaja P.、Likhite, Anjali P.、Chaudhary, Preeti M.

  DOI：——

  日期：——