stercurensin | 94388-75-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: stercurensin
• 英文别名: (E)-1-(2,4-dihydroxy-6-methoxy-3-methylphenyl)-3-phenylprop-2-en-1-one
• CAS: 94388-75-7
• 化学式: C₁₇H₁₆O₄
• 分子量: 284.312
• InChiKey: JUZVHLGKYJTCKP-CMDGGOBGSA-N

物化性质

• 物理描述：
  Solid
• 熔点：
  210-211°C

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  stercurensin 、 硫酸二甲酯 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 生成 2',4'-dimethoxy-6'-hydroxy-5'-C-methylchalcone
  参考文献：
  名称：

  Anjaneyulu, A. S. R.; Raju, S. Nooka, Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984, vol. 23, # 10, p. 1010 - 1011

  摘要：

  DOI：

文献信息

• CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS
  申请人：YOON Injoong

  公开号：US20120046353A1

  公开（公告）日：2012-02-23

  The present invention relates to a Cleistocalyx operculatus -derived compound having inhibitory activity against neuraminidase and to a composition for preventing and treating diseases caused by avian and swine influenza viruses and novel influenza viruses, comprising the compound as an active ingredient.
• [EN] ANTIVIRAL DRUG FOR AVIAN AND SWINE INFLUENZA AND NOVEL FLU, OBTAINED FROM CLEISTOCALYX OPERCULATUS<br/>[FR] MÉDICAMENT ANTIVIRAL POUR LA GRIPPE AVIAIRE ET PORCINE ET LA NOUVELLE GRIPPE, OBTENU À PARTIR DE CLEISTOCALYX OPERCULATUS
  申请人：CHOONG ANG VACCINE LAB

  公开号：WO2012023660A1

  公开（公告）日：2012-02-23

  본 발명은 크레이스토카릭스 오페르쿠라투스 유래의 뉴라미니데이즈 효소(neuraminidase)를 저해하는 화합물 및 이를 유효성분으로 포함하는 조류 및 돼지 인플루엔자와 신종플루의 예방과 치료에 사용하는 조성물에 관한 것이다.