2-(4-fluorophenyl)benzo[d]oxazol-5-ol | 847470-51-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(4-fluorophenyl)benzo[d]oxazol-5-ol
• 英文别名: 5-hydroxy-2-(p-fluorophenyl)benzoxazole；2-(4-fluorophenyl)-5-benzoxaz-5-ol；2-(4-Fluorophenyl)benzoxazol-5-ol；2-(4-fluorophenyl)-1,3-benzoxazol-5-ol
• CAS: 847470-51-3
• 化学式: C₁₃H₈FNO₂
• 分子量: 229.21
• InChiKey: DDAPYFMDZYRZOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  46.3
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-(4-fluorophenyl)-5-methoxybenzo[d]oxazole 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 反应 36.0h， 生成 2-(4-fluorophenyl)benzo[d]oxazol-5-ol
  参考文献：
  名称：

  [EN] SUBSTITUTED PIPERAZINE COMPOUNDS AND THEIR USE AS FATTY ACID OXIDATION INHIBITORS
  [FR] COMPOSES HETEROCYCLIQUES SUBSTITUES

  摘要：

  公开号：

  WO2004052887A3

文献信息

• Substituted heterocyclic compounds
  申请人：——

  公开号：US20040152890A1

  公开（公告）日：2004-08-05

  Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes.

  本发明涉及新型杂环衍生物，可用于治疗各种疾病状态，特别是心血管疾病，如心房和心室心律失常、间歇性跛行、普林兹梅特尔（变异型）心绞痛、稳定和不稳定性心绞痛、运动诱发性心绞痛、充血性心力衰竭和心肌梗塞。该化合物也可用于糖尿病的治疗。
• Alignment compounds
  申请人：Transitions Optical, Inc.

  公开号：US10875833B2

  公开（公告）日：2020-12-29

  The present invention relates to compounds represented by the following Formula (I). With reference to Formula (I), at least one of E1 and E2 independently is, or is independently substituted with, at least one reactive group, such as a (meth)acryloyl group. The compounds of the present invention can be used alone and/or in combination with polymers prepared from such compounds, such as to form or as one or more components of an alignment layer.

  本发明涉及下式（I）所代表的化合物。关于式（I），E1 和 E2 中的至少一个独立地是，或独立地被至少一个活性基团，如（甲基）丙烯酰基取代。本发明的化合物可单独使用和/或与由此类化合物制备的聚合物结合使用，例如形成对位层或作为对位层的一个或多个组分。
• Alignment polymers
  申请人：Transitions Optical, Inc.

  公开号：US11130912B2

  公开（公告）日：2021-09-28

  The present invention relates to polymers that include residues of at least one monomer represented by the following Formula (I). With reference to Formula (I), at least one of E1 and E2 independently is, or is independently substituted with, at least one reactive group, such as a (meth)acryloyl group. Monomers represented by Formula (I) and monomer residues thereof have alignment properties, such as photoalignment properties. The present invention also relates to alignment layers that include such polymers, and articles of manufacture, such as optical elements, that include one or more such alignment layers.

  本发明涉及包括由下式（I）代表的至少一种单体残留物的聚合物。关于式（I），E1 和 E2 中的至少一个独立地是，或独立地被至少一个活性基团取代，如（甲基）丙烯酰基。由式（I）代表的单体及其单体残基具有对位特性，例如光对位特性。本发明还涉及包括此类聚合物的配向层，以及包括一个或多个此类配向层的制造品，如光学元件。
• NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0623115A1

  公开（公告）日：1994-11-09
• EP0623115A4
  申请人：——

  公开号：EP0623115A4

  公开（公告）日：1995-01-11