leucodelphinidin | 126721-84-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: leucodelphinidin
• 英文别名: 3,4,5,7,3',4',5'-heptahydroxyflavan；2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,4,5,7-tetrol
• CAS: 126721-84-4
• 化学式: C₁₅H₁₄O₈
• 分子量: 322.271
• InChiKey: ZEACOKJOQLAYTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  151
• 氢给体数：
  7
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 leucodelphinidin 在 吡啶 作用下， 生成 3,5,7-triacetoxy-2-(3,4,5-triacetoxy-phenyl)-2H-chromene
  参考文献：
  名称：

  Laumas; Seshadri, Proceedings - Indian Academy of Sciences, Section A, 1959, # 49, p. 47,52

  摘要：

  DOI：

文献信息

• A study of leucoanthocyanidins of plants—I
  作者：A.K. Ganguly、T.R. Seshadri、P. Subramanian

  DOI：10.1016/0040-4020(58)80017-4

  日期：1958.1

  (Cleistanthus collinus) has been isolated, and its acetate and methyl ether have been prepared and their properties and reactions studied. It is found to be a (−)-leucodelphinidin (5:7:3′:4′:5′-pentahydroxyflavan-3:4-diol). a dextro-rotatory leucodelphinidin is found in the kino (gum) obtained from Eucalyptus pilularis and it gives a different series of derivatives.

  分离出Karada树皮（Cleistanthus collinus）的无色花色素，制备了其乙酸盐和甲基醚，并对其性质和反应进行了研究。发现是（-）-亮氨酸磷脂（5：7：3'：4'：5'-五羟基黄烷-3：4-二醇）。在从毛桉（Eucalyptus pilularis）获得的肌醇（口香糖）中发现了一种右旋的leucodelphinidin ，它提供了一系列不同的衍生物。
• Laumas; Seshadri, Journal Of Scientific and Industrial Research, 1958, vol. 17 B, p. 167
  作者：Laumas、Seshadri

  DOI：——

  日期：——
• [EN] DIHYDROMYRICETIN FOR THE TREATMENT OF DISEASES AND DISORDERS OF THE GLUTAMATERGIC SYSTEM<br/>[FR] DIHYDROMYRICÉTINE POUR LE TRAITEMENT DE MALADIES ET DE TROUBLES DU SYSTÈME GLUTAMATERGIQUE
  申请人：UNIV CALIFORNIA

  公开号：WO2014007853A1

  公开（公告）日：2014-01-09

  Disclosed herein are methods and compositions for treating a disease or disorder of the glutamatergic system, e.g., Alzheimer's disease, neuron damage and/or loss, and seizures, or a symptom thereof, e.g., decreased cognitive function, in a subject which comprises administering dihydromyricetin (DHM), an analog of DHM, or a metabolite of DHM to the subject.
• [EN] COMPOSITIONS AND METHODS FOR IMPROVING WELLNESS<br/>[FR] COMPOSITIONS ET MÉTHODES D'AMÉLIORATION DE BIEN-ÊTRE
  申请人：ADVANCED DELIVERY LABS LLC

  公开号：WO2020247961A1

  公开（公告）日：2020-12-10

  A composition for improving wellness of a human is provided herein. The composition includes, but is not limited to, a flavonoid. The composition further includes, but is not limited to, a prodrug of cysteine. The composition further includes, but is not limited to, a pharmaceutically acceptable carrier. The pharmaceutically acceptable carrier includes, but is not limited to, an ionic liquid to form a solubilizing matrix. The flavonoid exhibits an improved solubility in the pharmaceutically acceptable carrier in the presence of the solubilizing matrix as compared to solubility of a flavonoid in a pharmaceutically acceptable carrier substantially free of the solubilizing matrix.
• Laumas; Seshadri, Proceedings - Indian Academy of Sciences, Section A, 1959, # 49, p. 47,52
  作者：Laumas、Seshadri

  DOI：——

  日期：——