O¹,O²;O⁵,O⁶-diisopropylidene-4',5'-dihydro-spiro[α-D-3-deoxy-glucofuranose-3,3'-pyrazole] | 39682-01-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: O¹,O²;O⁵,O⁶-diisopropylidene-4',5'-dihydro-spiro[α-D-3-deoxy-glucofuranose-3,3'-pyrazole]
• 英文别名: (6S)-5c-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-(3ac,6rN,6ac)-3a,6a,4',5'-tetrahydro-spiro[furo[2,3-d][1,3]dioxole-6,3'-pyrazole]
• CAS: 39682-01-4
• 化学式: C₁₄H₂₂N₂O₅
• 分子量: 298.339
• InChiKey: GFIUCDGOBNZZJK-HRHGFQOTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.61
• 重原子数：
  21.0
• 可旋转键数：
  1.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  70.87
• 氢给体数：
  0.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  O¹,O²;O⁵,O⁶-diisopropylidene-4',5'-dihydro-spiro[α-D-3-deoxy-glucofuranose-3,3'-pyrazole] 生成 O⁵,O⁶-diacetyl-O¹,O²-isopropylidene-4',5'-dihydro-spiro[α-D-3-deoxy-glucofuranose-3,3'-pyrazole]
  参考文献：
  名称：

  D�riv�s C-glycosyliques. IX. Synth�se despiro-?2-isoxazolines et despiro-?1-pyrazolines � partir du d�soxy-3-di-O-isopropylid�ne 1, 2: 5, 6-m�thyl�ne-3-?-D-ribo-hexofurannose. Communication pr�liminaire

  摘要：

  AbstractTreatment of 3‐deoxy‐1, 2:5, 6‐di‐O‐isopropylidène‐3C‐méthylene‐α‐D‐ribo‐hexofuranose with aromatic nitrile oxides led to spiro‐Δ2‐isoxazolines, whereas a Δ1‐pyrazoline was obtained by reacting the same C‐methylenic sugar with diazomethane. Properties of these compounds, a new class of carbohydrates, and 5, 6‐di‐O‐acetyl derivatives thereof are described.

  DOI：

  10.1002/hlca.19720550811
• 作为产物：
  描述：

  重氮甲烷 、 O¹,O²;O⁵,O⁶-diisopropylidene-3-methylene-α-D-ribo-3-deoxy-hexofuranose 生成 O¹,O²;O⁵,O⁶-diisopropylidene-4',5'-dihydro-spiro[α-D-3-deoxy-glucofuranose-3,3'-pyrazole]
  参考文献：
  名称：

  D�riv�s C-glycosyliques. IX. Synth�se despiro-?2-isoxazolines et despiro-?1-pyrazolines � partir du d�soxy-3-di-O-isopropylid�ne 1, 2: 5, 6-m�thyl�ne-3-?-D-ribo-hexofurannose. Communication pr�liminaire

  摘要：

  AbstractTreatment of 3‐deoxy‐1, 2:5, 6‐di‐O‐isopropylidène‐3C‐méthylene‐α‐D‐ribo‐hexofuranose with aromatic nitrile oxides led to spiro‐Δ2‐isoxazolines, whereas a Δ1‐pyrazoline was obtained by reacting the same C‐methylenic sugar with diazomethane. Properties of these compounds, a new class of carbohydrates, and 5, 6‐di‐O‐acetyl derivatives thereof are described.

  DOI：

  10.1002/hlca.19720550811