dimethyl 4,4'-dimethoxybiphenyl-3,3'-dicarboxylate | 1008452-95-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dimethyl 4,4'-dimethoxybiphenyl-3,3'-dicarboxylate
• 英文别名: 3,3'-dicarbomethoxy-4,4'-dimethoxybiphenyl；Dimethyl 4,4'-dimethoxybiphenyl-3,3'-dicarboxylate；methyl 2-methoxy-5-(4-methoxy-3-methoxycarbonylphenyl)benzoate
• CAS: 1008452-95-6
• 化学式: C₁₈H₁₈O₆
• 分子量: 330.337
• InChiKey: AVVPCBDXQCUWBC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  dimethyl 4,4'-dimethoxybiphenyl-3,3'-dicarboxylate 在 potassium hydroxide 、 盐酸 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 6.0h， 以96%的产率得到4,4'-dimethoxy-3,3'-biphenyldicarboxylic acid
  参考文献：
  名称：

  Self-assembly of vesicles from the stacking of a dipodal F⋯H–N hydrogen bonded arylamide foldamer

  摘要：

  In this paper, we report the synthesis and self-assembling behavior of an F center dot center dot center dot H-N hydrogen bonding-induced arylamide-based dipodal foldamer. SEM, AFM. TEM, and XRD studies reveal that this preorganized oligomer stacks to form vesicles in methanol-chloroform (10-70%) binary solvents due to the strong stacking interaction of the folded segments and the supramolecular polymeric feature of the dipodal molecule in the stacked state. In contrast, a simple folded molecule can give rise to vesicles only when the chloroform content is 45-55%. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.10.073
• 作为产物：
  描述：

  蛋白银染试剂盒 在 铜 作用下， 以 甲醇 为溶剂， 反应 4.5h， 以63%的产率得到dimethyl 4,4'-dimethoxybiphenyl-3,3'-dicarboxylate
  参考文献：
  名称：

  Self-assembly of vesicles from the stacking of a dipodal F⋯H–N hydrogen bonded arylamide foldamer

  摘要：

  In this paper, we report the synthesis and self-assembling behavior of an F center dot center dot center dot H-N hydrogen bonding-induced arylamide-based dipodal foldamer. SEM, AFM. TEM, and XRD studies reveal that this preorganized oligomer stacks to form vesicles in methanol-chloroform (10-70%) binary solvents due to the strong stacking interaction of the folded segments and the supramolecular polymeric feature of the dipodal molecule in the stacked state. In contrast, a simple folded molecule can give rise to vesicles only when the chloroform content is 45-55%. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.10.073

文献信息

• A general gold-catalyzed direct oxidative coupling of non-activated arenes
  作者：Anirban Kar、Naveenkumar Mangu、Hanns Martin Kaiser、Matthias Beller、Man Kin Tse

  DOI：10.1039/b714928j

  日期：——

  A gold-catalyzed mild and general oxidative homo-coupling of arenes using PhI(OAc)2 as the oxidant is described (13 examples, 31-81% yield).

  描述了使用PhI（OAc）2作为氧化剂的芳烃金催化的轻度和一般氧化均质偶联（13个实例，收率31-81％）。
• Gold-catalyzed direct oxidative coupling reactions of non-activated arenes
  作者：Anirban Kar、Naveenkumar Mangu、Hanns Martin Kaiser、Man Kin Tse

  DOI：10.1016/j.jorganchem.2008.11.016

  日期：2009.2

  A general gold-catalyzed oxidative homo- and hetero-coupling of arenes in mild conditions is described. This reaction gives moderate to excellent yield using PhI(OAc)2 as an oxidant. The effects of temperature, solvent, oxidant and concentration of substrate in this process have also been studied in detail. The product identity and distribution as well as the substrate limitation give us insights into

  描述了在温和条件下一般的金催化的芳烃的氧化均质和异质偶联。使用PhI（OAc）2作为氧化剂，该反应可获得中等至极好的收率。还详细研究了温度，溶剂，氧化剂和底物浓度在此过程中的影响。产品的特性和分布以及底物的限制使我们对这种类型的金催化剂有了更深入的了解。取决于反应条件，金催化剂表现为简单的路易斯酸，其使用DIAD作为胺化试剂从芳烃中生成胺。
• Self-assembly of vesicles from the stacking of a dipodal F⋯H–N hydrogen bonded arylamide foldamer
  作者：Lu Wang、Ze-Yun Xiao、Jun-Li Hou、Gui-Tao Wang、Xi-Kui Jiang、Zhan-Ting Li

  DOI：10.1016/j.tet.2009.10.073

  日期：2009.12

  In this paper, we report the synthesis and self-assembling behavior of an F center dot center dot center dot H-N hydrogen bonding-induced arylamide-based dipodal foldamer. SEM, AFM. TEM, and XRD studies reveal that this preorganized oligomer stacks to form vesicles in methanol-chloroform (10-70%) binary solvents due to the strong stacking interaction of the folded segments and the supramolecular polymeric feature of the dipodal molecule in the stacked state. In contrast, a simple folded molecule can give rise to vesicles only when the chloroform content is 45-55%. (C) 2009 Elsevier Ltd. All rights reserved.