Chlor-tris-hydroxymethyl-benzyl-phosphonium | 4515-59-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Chlor-tris-hydroxymethyl-benzyl-phosphonium
• 英文别名: Benzyl[tris(hydroxymethyl)]phosphanium chloride；benzyl-tris(hydroxymethyl)phosphanium;chloride
• CAS: 4515-59-7
• 化学式: C₁₀H₁₆O₃P*Cl
• 分子量: 250.662
• InChiKey: FGTLTLMXUFHMOG-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.94
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Chlor-tris-hydroxymethyl-benzyl-phosphonium 在 三乙胺 作用下， 生成 tribenzylphosphine oxide
  参考文献：
  名称：

  Petrov,K.A. et al., Journal of general chemistry of the USSR, 1962, vol. 32, # 2, p. 542 - 545

  摘要：

  DOI：
• 作为产物：
  描述：

  聚合甲醛 、 benzylphosphine 在 盐酸 作用下， 以 四氢呋喃 为溶剂， 生成 Chlor-tris-hydroxymethyl-benzyl-phosphonium
  参考文献：
  名称：

  Assmann, Bernd; Angermaier, Klaus; Paul, Martin, Chemische Berichte, 1995, vol. 128, # 9, p. 891 - 900

  摘要：

  DOI：

文献信息

• Versatile Synthesis of P^R₂N^R′₂ Ligands for Molecular Electrocatalysts with Pendant Bases in the Second Coordination Sphere
  作者：Michael D. Doud、Kyle A. Grice、Alyssia M. Lilio、Candace S. Seu、Clifford P. Kubiak

  DOI：10.1021/om201168h

  日期：2012.2.13

  Two 1,5-diaza-3,7-diphosphacyclooctane (P2N2) ligands with alkyl-substituted phosphines have been synthesized via a versatile method that allows for improved control of the phosphine substituent. The methyl- and benzyl-substituted phosphine P2N2 ligands ((P2N2Ph)-N-Me and (P2N2Ph)-N-Bn) were synthesized and characterized by P-31H-1} NMR, H-1 NMR, and elemental analysis, and their corresponding [Ni((P2N2Ph)-N-R)(2)](BF4)(2) complexes were synthesized and characterized by P-31H-1) NMR, H-1 NMR, and electrochemistry. The structure of the complex [Ni((P2N2Ph)-N-Me)(2)](CF3SO3)(2) was characterized by X-ray crystallography.
• Investigations into the Oxidative Stability of Hydroxymethyl- and Bis(Hydroxymethyl)-Phosphines
  作者：D. V. Griffiths、H. J. Groombridge、M. C. Salt

  DOI：10.1080/10426500701761417

  日期：2008.1.14

  Polydentate ligands containing the bis(hydroxymethyl)phosphine unit have been reported to exhibit enhanced oxidative stability, which would make them attractive for use in Tc-99m-radiopharmaceutical imaging agents. Benzylethyl(hydroxymethyl)phosphine, benzylbis(hydroxymethyl)phosphine and benzyldiethylphosphine were prepared in order to investigate the origin of this oxidative stability. Little evidence was found to indicate that the hydroxymethylphosphines show an enhanced level of stability, but it was demonstrated that the reaction conditions employed in their preparation generated a number of closely related by-products, which are likely to limit the usefulness of the hydroxymethylphosphines in commercial radiopharmaceutical applications.
• Petrov,K.A. et al., Journal of general chemistry of the USSR, 1962, vol. 32, # 2, p. 542 - 545
  作者：Petrov,K.A. et al.

  DOI：——

  日期：——
• Assmann, Bernd; Angermaier, Klaus; Paul, Martin, Chemische Berichte, 1995, vol. 128, # 9, p. 891 - 900
  作者：Assmann, Bernd、Angermaier, Klaus、Paul, Martin、Riede, Juergen、Schmidbaur, Hubert

  DOI：——

  日期：——