4,4,5,5,6,6,7,7,8,8,9,9-Dodecafluoro-undecan-1-ol | 350245-88-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4,4,5,5,6,6,7,7,8,8,9,9-Dodecafluoro-undecan-1-ol
• 英文别名: 4,4,5,5,6,6,7,7,8,8,9,9-Dodecafluoroundecan-1-ol
• CAS: 350245-88-4
• 化学式: C₁₁H₁₂F₁₂O
• 分子量: 388.197
• InChiKey: CGNAKMIQGOFBIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  13

反应信息

• 作为反应物：
  描述：

  4,4,5,5,6,6,7,7,8,8,9,9-Dodecafluoro-undecan-1-ol 在 TEA 、 三氯氧磷 、 水 作用下， 以 乙醚 为溶剂， 反应 2.0h， 以60%的产率得到Phosphoric acid mono-(4,4,5,5,6,6,7,7,8,8,9,9-dodecafluoro-undecyl) ester
  参考文献：
  名称：

  Synthesis and preliminary assessments of hybrid hydrocarbon–fluorocarbon anionic and non-ionic surfactants

  摘要：

  We describe the synthesis and preliminary physico-chemical assessments of ionic and non-ionic hybrid hydrofluorocarbon amphiphiles. Monoreduction reaction of the symmetrical starting material 1,10-diiodo-3,3,4,4,5,5,6,6,7,7,8,8-dodecafluorodecane provides the ethyl terminated fluorocarbon chains. These non-symmetrical hydrofluorocarbon surfactants contain an ethyl segment, a fluorocarbon core and either nonionic or anionic polar heads (sulfate. sulfonate, phosphate. carboxylate or glycosidic groups). The lactobionolactone can be reacted with hydrofluorocarbon amines to obtain the non-ionic hydrophilic moiety whereas the anionic heads come from monoiodo and/or hydroxyl hydrofluorocarbon substrates. The critical micellar concentration (CMC) values of these novel surfactants were determined by surface tension and conductivity measurements. The results are compared to those measured with fluorinated homologues previously described. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00506-8
• 作为产物：
  描述：

  4,4,5,5,6,6,7,7,8,8,9,9-Dodecafluoro-undecanoic acid 在 lithium aluminium tetrahydride 、 盐酸 作用下， 以 乙醚 、 水 为溶剂， 反应 6.0h， 以99%的产率得到4,4,5,5,6,6,7,7,8,8,9,9-Dodecafluoro-undecan-1-ol
  参考文献：
  名称：

  Synthesis and preliminary assessments of hybrid hydrocarbon–fluorocarbon anionic and non-ionic surfactants

  摘要：

  We describe the synthesis and preliminary physico-chemical assessments of ionic and non-ionic hybrid hydrofluorocarbon amphiphiles. Monoreduction reaction of the symmetrical starting material 1,10-diiodo-3,3,4,4,5,5,6,6,7,7,8,8-dodecafluorodecane provides the ethyl terminated fluorocarbon chains. These non-symmetrical hydrofluorocarbon surfactants contain an ethyl segment, a fluorocarbon core and either nonionic or anionic polar heads (sulfate. sulfonate, phosphate. carboxylate or glycosidic groups). The lactobionolactone can be reacted with hydrofluorocarbon amines to obtain the non-ionic hydrophilic moiety whereas the anionic heads come from monoiodo and/or hydroxyl hydrofluorocarbon substrates. The critical micellar concentration (CMC) values of these novel surfactants were determined by surface tension and conductivity measurements. The results are compared to those measured with fluorinated homologues previously described. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00506-8