1-(5-bromopentyloxy)-4-[(E)-2-nitrovinyl]benzene | 1256500-28-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-(5-bromopentyloxy)-4-[(E)-2-nitrovinyl]benzene
• 英文别名: (E)-1-(5-bromopentyloxy)-4-(2-nitrovinyl)benzene；1-(5-bromopentoxy)-4-[(E)-2-nitroethenyl]benzene
• CAS: 1256500-28-3
• 化学式: C₁₃H₁₆BrNO₃
• 分子量: 314.179
• InChiKey: OPZNKMKSIHCZGZ-CSKARUKUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,5-二溴戊烷 在 2-氨基乙醇,甲酸 、 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 21.0h， 生成 1-(5-bromopentyloxy)-4-[(E)-2-nitrovinyl]benzene
  参考文献：
  名称：

  Ambiphilic Dual Activation Role of a Task-Specific Ionic Liquid: 2-Hydroxyethylammonium Formate as a Recyclable Promoter and Medium for the Green Synthesis of β-Nitrostyrenes

  摘要：

  A cost-effective task-specific ionic liquid, 2-hydroxyethyl ammonium formate, efficiently promotes the condensation of nitroalkanes with various aldehydes to produce beta-nitrostyrenes in high to excellent yields at room temperature. This reaction does not involve any hazardous organic solvent and toxic catalyst. The ionic liquid is recovered and recycled for subsequent reactions. In addition, a novel mechanism has been proposed invoking ambiphilic dual activation influence of the ionic liquid.

  DOI：

  10.1021/jo101696z

文献信息

• Ambiphilic Dual Activation Role of a Task-Specific Ionic Liquid: 2-Hydroxyethylammonium Formate as a Recyclable Promoter and Medium for the Green Synthesis of β-Nitrostyrenes
  作者：Abdolhamid Alizadeh、Mohammad M. Khodaei、Ali Eshghi

  DOI：10.1021/jo101696z

  日期：2010.12.3

  A cost-effective task-specific ionic liquid, 2-hydroxyethyl ammonium formate, efficiently promotes the condensation of nitroalkanes with various aldehydes to produce beta-nitrostyrenes in high to excellent yields at room temperature. This reaction does not involve any hazardous organic solvent and toxic catalyst. The ionic liquid is recovered and recycled for subsequent reactions. In addition, a novel mechanism has been proposed invoking ambiphilic dual activation influence of the ionic liquid.