(3R,4S,5S)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3,4-triyl tribenzoate | 212499-87-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (3R,4S,5S)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3,4-triyl tribenzoate
• CAS: 212499-87-1
• 化学式: C₃₃H₂₆O₉
• 分子量: 566.564
• InChiKey: SVVKRZQAFRVDED-ZWWSUPLXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.88
• 重原子数：
  42.0
• 可旋转键数：
  9.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  114.43
• 氢给体数：
  0.0
• 氢受体数：
  9.0

反应信息

• 作为反应物：
  描述：

  (3R,4S,5S)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3,4-triyl tribenzoate 在 氢溴酸 作用下， 以 溶剂黄146 为溶剂， 以50%的产率得到2,3,4-tri-O-benzoyl-β-L-arabinopyranosyl bromide
  参考文献：
  名称：

  Synthesis and Testing of New Modified Nucleosides

  摘要：

  New efficient routes for the high-yielding synthesis of several classes of modified nucleosides have been developed. We have prepared both the D- and L-enantiomers of the methylene-expanded oxetanocin isonucleosides 1a-e and the L-2',3'-dideoxy isonucleosides 2abc (both the oxa and thia analgoues) as well as new routes for the preparation of L-ribose and 2-deoxy L-ribose 3ab and their modified nucleosides 4.

  DOI：

  10.1080/15257779908041490
• 作为产物：
  描述：

  L-arabinose 、 苯甲酰氯 以 吡啶 为溶剂， 生成 (3R,4S,5S)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3,4-triyl tribenzoate
  参考文献：
  名称：

  Synthesis and Testing of New Modified Nucleosides

  摘要：

  New efficient routes for the high-yielding synthesis of several classes of modified nucleosides have been developed. We have prepared both the D- and L-enantiomers of the methylene-expanded oxetanocin isonucleosides 1a-e and the L-2',3'-dideoxy isonucleosides 2abc (both the oxa and thia analgoues) as well as new routes for the preparation of L-ribose and 2-deoxy L-ribose 3ab and their modified nucleosides 4.

  DOI：

  10.1080/15257779908041490