N-[6-[(2-叠氮乙酰基)氨基]吡啶-2-基]十二烷酰胺 | 412024-32-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N-[6-[(2-叠氮乙酰基)氨基]吡啶-2-基]十二烷酰胺
• 英文名称: 2-azidoacetylamino-6-lauroylaminopyridine
• 英文别名: 2-azidoacetanoylamino-6-lauroylaminopyridine；N-[6-(2-Azidoacetamido)pyridin-2-YL]dodecanamide；N-[6-[(2-azidoacetyl)amino]pyridin-2-yl]dodecanamide
• CAS: 412024-32-9
• 化学式: C₁₉H₃₀N₆O₂
• 分子量: 374.486
• InChiKey: JFHQXDXJZLTCBB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  27
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  85.4
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  足球烯 、 N-[6-[(2-叠氮乙酰基)氨基]吡啶-2-基]十二烷酰胺 以 氯苯 为溶剂， 反应 72.0h， 以21%的产率得到
  参考文献：
  名称：

  Self-Assembly and Characterization of Supramolecular [60]Fullerene-Containing 2,6-Diacylamidopyridine with Uracil Derivative by Hydrogen-Bonding Interaction

  摘要：

  [GRAPHICS]Novel self-assembly systems of uracil derivatives with organofullerene by a three-point hydrogen-bonding interaction were designed and established. The formation of hydrogen bonding was established by H-1 NMR studies in CDCl3.

  DOI：

  10.1021/ol025614i
• 作为产物：
  描述：

  6-amino-2-dodecanoylaminopyridine 在 sodium azide 作用下， 以 四氢呋喃 、 乙醇 、 水 为溶剂， 反应 48.0h， 生成 N-[6-[(2-叠氮乙酰基)氨基]吡啶-2-基]十二烷酰胺
  参考文献：
  名称：

  Self-Assembly and Characterization of Supramolecular [60]Fullerene-Containing 2,6-Diacylamidopyridine with Uracil Derivative by Hydrogen-Bonding Interaction

  摘要：

  [GRAPHICS]Novel self-assembly systems of uracil derivatives with organofullerene by a three-point hydrogen-bonding interaction were designed and established. The formation of hydrogen bonding was established by H-1 NMR studies in CDCl3.

  DOI：

  10.1021/ol025614i

文献信息

• Synthesis and Characterization of Three Novel [60]Fullerene Derivatives toward Self-Assembled Nanoparticles through Interaction of Hydrogen Bonding
  作者：Shengqiang Xiao、Yuliang Li、Hongjuan Fang、Hongmei Li、Huibiao Liu、Zhiqiang Shi、Lei Jiang、Daoben Zhu

  DOI：10.1021/ol026386v

  日期：2002.9.1

  [GRAPHICS]Three novel fullerene derivatives bearing a 2,6-bis(acylamino) pyridine unit as a hydrogen bonding motif displaying a dimerization tendency were synthesized and characterized by the cycloaddition reaction of alkyl azide to [60]fullerene. An SEM image of the dimerization system of compound 1 indicated spherical particles having a mean diameter of 15 nm with a rather narrow size distribution.
• Self-Assembly and Characterization of Supramolecular [60]Fullerene-Containing 2,6-Diacylamidopyridine with Uracil Derivative by Hydrogen-Bonding Interaction
  作者：Zhiqiang Shi、Yuliang Li、Haofei Gong、Minghua Liu、Shengxiong Xiao、Huibiao Liu、Hongmei Li、Shengqiang Xiao、Daoben Zhu

  DOI：10.1021/ol025614i

  日期：2002.4.1

  [GRAPHICS]Novel self-assembly systems of uracil derivatives with organofullerene by a three-point hydrogen-bonding interaction were designed and established. The formation of hydrogen bonding was established by H-1 NMR studies in CDCl3.