A silicon-mediated synthesis of novel 5-substituted 2,4-dimethoxypyrimidines and 5-substituted uracils
作者:Nitya G. Kundu、Biswajit Das、Anjali Majumdar、Lakshmi N. Choudhuri
DOI:10.1016/s0040-4039(00)96775-3
日期:1987.1
A highly efficient and general method for the synthesis of 5-(2-acylethynyl)-2,4-dimethoxypyrimidines starting from 2,4-dimethoxy-5-/2-(trimethylsilyl)ethynyl/pyrimidine is described. The 5-(2-acylethynyl)-2,4-dimechoxypyrimidines have been converted to 5-(2-acyl-1-iodovinyl) uracils and 5-(2-acylethynyl) uracils.
Synthesis of 5-(acylethynyl)uracils and their corresponding 2′-deoxyribonucleosides through palladium-catalysed reactions
作者:Nitya G. Kundu、Swapan K. Dasgupta
DOI:10.1039/p19930002657
日期:——
Good yields of the title uracils were obtained by using the palladium-catalysed reaction between 5-iodo-2,4-dimethoxypyrimidine and substituted propargylic alcohols rather than the corresponding ketones. The same strategy works for coupling with the 5-iodo-2'-deoxyuridines.
Kundu, Nitya G.; Chaudhuri, Lakshmi, Journal of the Chemical Society. Perkin transactions I, 1991, # 7, p. 1677 - 1682
作者:Kundu, Nitya G.、Chaudhuri, Lakshmi
DOI:——
日期:——
Kundu, Nitya G.; Choudhuri, Lakshmi N.; Das, Biswajit, Journal of the Chemical Society. Perkin transactions I, 1989, p. 1165 - 1166