O2-甲基-D-半乳糖 | 4060-33-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: O2-甲基-D-半乳糖
• 英文名称: 2-O-Methyl-D-galactose
• 英文别名: 2-O-Methyl-D-galaktose；2-o-Methylgalactose；(2R,3S,4S,5R)-3,4,5,6-tetrahydroxy-2-methoxyhexanal
• CAS: 4060-33-7
• 化学式: C₇H₁₄O₆
• 分子量: 194.185
• InChiKey: QRAXLHLYZJCAKB-JRTVQGFMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.9
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  O2-甲基-D-半乳糖 、 水 、 potassium acetate 、 lead(IV) tetraacetate 、 溶剂黄146 生成 甲酸
  参考文献：
  名称：

  Structure of Reducing Disaccharides by Lead Tetraacetate Oxidation

  摘要：

  DOI：

  10.1021/ac60099a019
• 作为产物：
  描述：

  methyl 2-O-methyl-β-D-galactopyranoside 在 硫酸 作用下， 生成 O2-甲基-D-半乳糖
  参考文献：
  名称：

  d-理想a d（+）-半乳糖

  摘要：

  DOI：

  10.1002/hlca.19450280102

文献信息

• Separation process
  申请人：Heikkila Heikki

  公开号：US20050096464A1

  公开（公告）日：2005-05-05

  The invention relates to a process of recovering arabinose and optionally other monosaccharides from vegetable fiber rich in heteropolymeric arabinose, such as gum arabic. Said other monosaccharides are typically selected from galactose and rhamnose. The process of the invention comprises controlled hydrolysis of the arabinose-rich vegetable fiber and fractionation of the hydrolysis product to obtain a fraction enriched in arabinose and optionally other product fractions followed by crystallization of arabinose. The invention also relates to a novel method of crystallizing arabinose from biomass-derived material. Furthermore, the invention relates to novel crystalline L-arabinose.

  本发明涉及一种从富含异聚糖阿拉伯糖的植物纤维中回收阿拉伯糖和可选的其他单糖的过程，例如阿拉伯胶。所述其他单糖通常选自半乳糖和鼠李糖。本发明的过程包括对富含阿拉伯糖的植物纤维进行控制水解，分馏水解产物以获得富含阿拉伯糖和可选的其他产物分馏，然后结晶阿拉伯糖。本发明还涉及一种从生物质衍生材料中结晶阿拉伯糖的新方法。此外，本发明还涉及新颖的结晶L-阿拉伯糖。
• Macrolide antibiotics, process for their preparation, inter alia by fermentation, and pharmaceutical compositions containing them
  申请人：SCHERING CORPORATION

  公开号：EP0033433A1

  公开（公告）日：1981-08-12

  Disclosed are novel macrolide antibiotics of the general formula wherein R is H or OH; M is 0 or (H,OH); Z is the group of formula II, -CH7OH or groups which may be derived therefrom; A represents a double bond between carbon atoms of positions 12 and 13 or, together with the carbon atoms of positions 12 and 13, an oxirane ring. B represents a double bond between the carbon atoms of positions 10 and 11 or together with the carbon atoms of positions 10 and 11 the group -CH2-CH(O')-or-CH2-CH(O2)- and the non-toxic pharmaceutically acceptable ester and acid addition salts thereof. The novel antibiotic complex designated antibiotic AR-5 of the formula (falling within the scope of formula I), wherein R is hydrogen or hydroxy, and A represents a double bond or together with the carbon atoms of positions 12 and 13 an oxirane ring, can be produced by fermentation of a new species of the genus Micromonospora. which is Micromonospora Polytrota (e.g. NRRL 12066) The other compounds of formula I can be derived from the compounds of antibiotic AR-5 complex The compounds shown antibacterial activity. The gentamycine C complex is also produced by mic- romonospora polytrota NRRL 12066

  公开了通式如下的新型大环内酯类抗生素 其中 R 是 H 或 OH；M 是 0 或 (H，OH)；Z 是式 II 的基团、 -A 代表位置 12 和 13 的碳原子之间的双键，或与位置 12 和 13 的碳原子一起构成环氧乙烷环。B 代表位置 10 和 11 的碳原子之间的双键，或与位置 10 和 11 的碳原子一起代表基团-CH2-CH(O')-或-CH2-CH(O2)-及其无毒的药学上可接受的酯和酸加成盐。 新型抗生素复合物命名为抗生素 AR-5，其式为 (属于式 I 的范围)，其中 R 是氢或羟基，A 代表双键或与第 12 位和第 13 位的碳原子一起代表环氧乙烷环，可通过小孢子菌属的一个新物种发酵制得，该新物种是 Polytrota 小孢子菌(例如 NRRL 12066)。 显示出抗菌活性的化合物。NRRL 12066 也能产生庆大霉素 C 复合物。
• Method of harvesting rare cells from blood products
  申请人：PALL CORPORATION

  公开号：EP1690930A1

  公开（公告）日：2006-08-16

  The invention relates to a method of harvesting rare cells from a blood product. In one embodiment, the rare cells comprise mononuclear cells and in another embodiment the cells comprise dendritic cells. The method comprises contacting the blood product with a porous medium and selectively retaining the rare cells on the porous medium. The porous medium is contacted with an elution fluid which in one embodiment is a nutrient rich elution fluid and in another embodiment is an elution fluid at a temperature between about 5-37°C. The rare cells are selectively eluted from the porous medium.

  本发明涉及一种从血液制品中提取稀有细胞的方法。在一个实施方案中，稀有细胞包括单核细胞，在另一个实施方案中，细胞包括树突状细胞。该方法包括将血液制品与多孔介质接触，并选择性地将稀有细胞保留在多孔介质上。多孔介质与洗脱液接触，在一个实施方案中，洗脱液是一种富含营养物质的洗脱液，在另一个实施方案中，洗脱液的温度大约在 5-37°C 之间。稀有细胞被选择性地从多孔介质中洗脱出来。
• Advanced drug development and manufacturing
  申请人：Los Alamos National Security, LLC

  公开号：EP2511844A2

  公开（公告）日：2012-10-17

  There is described an apparatus for measuring protein characteristics comprising an X-ray fluorescence (XRF) spectrometer comprising a source of polychromatic X-rays, an X-ray detector, a protein, a molecule that has been exposed to and at least weakly binds to the protein, a plurality of X-ray fluorescence signal data obtained by irradiating chemical elements in the protein and molecule with the polychromatic X-rays and a security system for maintaining records for the data from the plurality of X-ray fluorescence signal measurements. There is also described an x-ray microscope for measuring a sample.

  描述了一种测量蛋白质特性的仪器，该仪器包括一个 X 射线荧光 (XRF) 光谱仪，其中包括一个多色 X 射线源、一个 X 射线探测器、一个蛋白质、一个已暴露于该蛋白质并至少与该蛋白质弱结合的分子、通过用多色 X 射线照射蛋白质和分子中的化学元素而获得的多个 X 射线荧光信号数据，以及一个用于维护多个 X 射线荧光信号测量数据记录的安全系统。此外，还介绍了一种用于测量样品的 X 射线显微镜。
• Immunomodulating compositions and uses therefor
  申请人：Ralph, Stephen John

  公开号：EP2591786A1

  公开（公告）日：2013-05-15

  The present invention discloses immunomodulating compositions. More particularly, the present invention discloses compositions comprising an immune-modulating agent and a lectin-interactive agent, which are useful for stimulating and prolonging host immune cell responses. The compositions of the present invention are particularly useful in the treatment and/or prophylaxis of a range of conditions including pathogenic infections, autoimmune diseases, transplant rejection, graft versus host disease, allergies, inflammatory disease, as well as cancers and tumours.

  本发明公开了免疫调节组合物。更具体地说，本发明公开了包含免疫调节剂和凝集素活性剂的组合物，这些组合物有助于刺激和延长宿主免疫细胞反应。本发明的组合物特别适用于治疗和/或预防一系列疾病，包括病原体感染、自身免疫性疾病、移植排斥反应、移植物抗宿主疾病、过敏、炎症性疾病以及癌症和肿瘤。