叔-丁基N-(1-乙基-3-羟基-丙基)氨基甲酸酯 | 135065-68-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 叔-丁基N-(1-乙基-3-羟基-丙基)氨基甲酸酯
• 英文名称: 3-(t-butoxycarbonylamino)pentanol
• 英文别名: 3-(N-BOC-amino)-pentan-1-ol；tert-Butyl (1-hydroxypentan-3-yl)carbamate；tert-butyl N-(1-hydroxypentan-3-yl)carbamate
• CAS: 135065-68-8
• 化学式: C₁₀H₂₁NO₃
• 分子量: 203.282
• InChiKey: BUQMELIOJVZHGM-UHFFFAOYSA-N

物化性质

• 沸点：
  317.1±25.0 °C(Predicted)
• 密度：
  0.997±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  7-羟基-3,4,8-三甲基香豆素 、 叔-丁基N-(1-乙基-3-羟基-丙基)氨基甲酸酯 、 偶氮二甲酸二乙酯 在 三苯基膦 作用下， 以 二氯甲烷 为溶剂， 生成 7-[(RS)-3-(t-butoxycarbonylamino)pentoxy]-3,4,8-trimethylcoumarin
  参考文献：
  名称：

  Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders

  摘要：

  公开号：

  EP0411912B1
• 作为产物：
  描述：

  二碳酸二叔丁酯 、 3-aminopentan-1-ol 以 四氢呋喃 、 正己烷 、 乙酸乙酯 为溶剂， 生成 叔-丁基N-(1-乙基-3-羟基-丙基)氨基甲酸酯
  参考文献：
  名称：

  Ornithine decarboxylase inhibiting branched aminooxy amino alkane

  摘要：

  化学式（I）中的化合物，其中（a）R.sub.1、R.sub.2、R.sub.3、R.sub.4、R.sub.5和R.sub.6中的四个基团为氢，其余基团独立地分别为每种情况下为C.sub.1-C.sub.2烷基，这些基团与同一碳原子或两个不同的碳原子结合，或者（b）R.sub.1、R.sub.2、R.sub.3、R.sub.4、R.sub.5和R.sub.6中的五个基团为氢，另一个基团为C.sub.1-C.sub.2烷基或羟甲基，或其盐。这些化合物的化学式（I）及其盐是鸟氨酸脱羧酶抑制剂。

  公开号：

  US05610195A1

文献信息

• Diamine Derivative, Process of Preparation Thereof, and Fungicide Comprising Diamine Derivative as an Active Ingredient
  申请人：Kakimoto Takeshi

  公开号：US20070244153A1

  公开（公告）日：2007-10-18

  It is an object of the invention to provide a novel fungicide which exhibits a wide controlling spectrum against pathogens of various crops, and solves the toleration problem. The diamine derivative represented by the formula (1) and a process for preparation of the same, fungicides comprising the same as an active ingredient are disclosed: [wherein R1 is substituents such as an alkyl group having 1 to 6 carbon atoms and the like, R2 and R5 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, R3 and R4 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, or R3 and R4 may be bonded to each other to form a hydrocarbon ring having 3 to 6 carbon atoms, R6, R7, R8 and R9 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, R10 is a substituent such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, A is an oxygen atom or a sulfur atom, and Q is an aryl group or a heterocycle].

  本发明的目的是提供一种新型杀菌剂，该杀菌剂对各种作物的病原体具有广泛的控制谱，并解决了容忍问题。本发明公开了由式（1）表示的二胺衍生物及其制备方法，以及包含其作为活性成分的杀菌剂：[其中，R1是取代基，例如具有1到6个碳原子的烷基等，R2和R5各自独立地是氢原子、具有1到6个碳原子的烷基等取代基，R3和R4各自独立地是氢原子、具有1到6个碳原子的烷基等取代基，或者R3和R4可以结合在一起形成具有3到6个碳原子的碳氢环，R6、R7、R8和R9各自独立地是氢原子、具有1到6个碳原子的烷基等取代基，R10是氢原子、具有1到6个碳原子的烷基等取代基，A是氧原子或硫原子，Q是芳基或杂环]。
• ARYLMETHYLEN SUBSTITUTED N-ACYL-Y-AMINOALCOHOLS
  申请人：Wortmann Lars

  公开号：US20080287493A1

  公开（公告）日：2008-11-20

  The present invention relates to arylmethylen substituted N-acyl-Y-aminoalcohols of the general formula I in which Q, X, W, R1, R2, R3, R4 and R5 have the meaning as defined in the description. The compounds according to the invention are effective FSH modulators and can be used for example for fertility regulation in men or in women.

  本发明涉及一般式I的芳基亚甲基取代的N-酰基-Y-氨基醇，其中Q、X、W、R1、R2、R3、R4和R5的含义如描述中所定义。根据本发明的化合物是有效的FSH调节剂，例如可用于男性或女性的生育调节。
• DIAMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME AND FUNGICIDE CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1770085A1

  公开（公告）日：2007-04-04

  It is an object of the invention to provide a novel fungicide which exhibits a wide controlling spectrum against pathogens of various crops, and solves the toleration problem. The diamine derivative represented by the formula (1) and a process for preparation of the same, fungicides comprising the same as an active ingredient are disclosed: [wherein R1 is substituents such as an alkyl group having 1 to 6 carbon atoms and the like, R2 and R5 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, R3 and R4 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, or R3 and R4 may be bonded to each other to form a hydrocarbon ring having 3 to 6 carbon atoms, R6, R7, R8 and R9 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, R10 is a substituent such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, A is an oxygen atom or a sulfur atom, and Q is an aryl group or a heterocycle].

  本发明的目的是提供一种新型杀菌剂，该杀菌剂对各种作物的病原体具有广泛的控制谱，并解决了耐受性问题。 本发明公开了式 (1) 所代表的二胺衍生物及其制备方法，以及以二胺衍生物为有效成分的杀菌剂： 其中 R1 是取代基，如具有 1 至 6 个碳原子的烷基等；R2 和 R5 各自独立地是取代基，如氢原子、具有 1 至 6 个碳原子的烷基等；R3 和 R4 各自独立地是取代基，如氢原子、具有 1 至 6 个碳原子的烷基等、R6、R7、R8 和 R9 各自独立地为取代基，如氢原子、具有 1-6 个碳原子的烷基等，R10 为取代基，如氢原子、具有 1-6 个碳原子的烷基等，A 为氧原子或硫原子，Q 为芳基或杂环]。
• ORNITHINE DECARBOXYLASE INHIBITING BRANCHED AMINOOXY AMINO ALKANE DERIVATIVES
  申请人：CIBA-GEIGY AG

  公开号：EP0644873B1

  公开（公告）日：1997-03-12
• US5610195A
  申请人：——

  公开号：US5610195A

  公开（公告）日：1997-03-11