Hydroxy-resorcein | 71939-12-3

• 物质功能分类: 生物化工 - 生化试剂 - 生物染料
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: Hydroxy-resorcein
• 英文别名: 2,8-Bis(2,4-dihydroxyphenyl)-7-hydroxyphenoxazin-3-one
• CAS: 71939-12-3
• 化学式: C₂₄H₁₅NO₇
• 分子量: 429.386
• InChiKey: VBELMRDAQMYTOU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  32
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  140
• 氢给体数：
  5
• 氢受体数：
  8

安全信息

• 安全说明：
  S24/25

反应信息

• 作为产物：
  描述：

  2,4-二甲氧基苯硼酸 在 palladium on activated charcoal 、 palladium diacetate lead(IV) tetraacetate 、 三溴化硼 、 potassium carbonate 、 三苯基膦 作用下， 以 1,4-二氧六环 、 乙醇 、 二氯甲烷 、 水 、 溶剂黄146 、 乙酸乙酯 为溶剂， 反应 38.5h， 生成 Hydroxy-resorcein
  参考文献：
  名称：

  [EN] PHENOXAZINONES OR PHENOTHIAZONES AS INHIBITORS OF AMYLOID FORMATION
  [FR] PHÉNOXAZINONES OU PHÉNOTHIAZONES EN TANT QU'INHIBITEURS DE FORMATION D'AMYLOÏDE

  摘要：

  本发明涉及用于治疗淀粉样疾病（如阿尔茨海默病）的化合物。此外，这些化合物还可用于成像淀粉样沉积物。

  公开号：

  WO2012136655A1

文献信息

• Phenoxazinones or phenothiazones as inhibitors of amyloid formation
  申请人：Max-Delbrück-Centrum für Molekulare Medizin

  公开号：EP2508186A1

  公开（公告）日：2012-10-10

  The present invention relates to compounds useful in the treatment of amyloid diseases, such as Alzheimer's disease. Further, the compounds are useful for imaging amyloid deposits.

  本发明涉及对淀粉样疾病（如阿尔茨海默病）治疗中有用的化合物。此外，这些化合物还可用于成像淀粉样沉积物。
• Musso,H. et al., Chemische Berichte, 1963, vol. 96, p. 1579 - 1587
  作者：Musso,H. et al.

  DOI：——

  日期：——
• Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly
  申请人：Varaprasad V. Desaraju

  公开号：US20070184284A1

  公开（公告）日：2007-08-09

  An exterior electrochromic reflective mirror element for a vehicular exterior rearview mirror assembly comprises an electrochromic cross-linked polymeric solid film disposed between a first substrate and a second substrate. The electrochromic cross-linked polymeric solid film contacts a transparent conductive layer of the first substrate and a conductive layer comprising a metallic reflective layer of the second substrate. A visual indicator display is disposed to the rear of said second substrate and is part of a blind spot detection and display system and is actuated to emit light responsive to a detection of another overtaking vehicle in a side lane. Light emitted by the visual indicator display passes through the second substrate, through the electrochromic cross-linked polymeric solid film and through the first substrate to be viewed by a driver of the vehicle equipped with the exterior electrochromic reflective mirror element.
• VEHICULAR EXTERIOR MIRROR
  申请人：Varaprasad V. Desaraju

  公开号：US20080094685A1

  公开（公告）日：2008-04-24

  An exterior mirror suitable for use in a vehicular exterior rearview mirror assembly includes a reflective mirror element having a light transmitting substrate with a mirror reflector having a metallic reflective layer coated thereon. A visual indicator display is disposed to the rear of the light transmitting substrate and actuated to emit light when powered. Light emitted by light sources of the display passes through the light transmitting substrate so as to be viewed by a driver of the vehicle equipped with the reflective mirror element. The mirror element has portions of the metallic reflective layer at least partially removed by laser scribing to establish at least partially light transmissive portions of the mirror reflector so that light emitted by light sources, when powered, passes through the respective at least partially light transmissive portions to be viewed by a viewer viewing from the front of the reflective mirror element.
• EXTERIOR REFLECTIVE MIRROR ELEMENT FOR A VEHICULAR REARVIEW MIRROR ASSEMBLY
  申请人：Varaprasad Desaraju V.

  公开号：US20100053723A1

  公开（公告）日：2010-03-04

  An exterior reflective mirror element suitable for a vehicle includes a transparent glass substrate having a reflector and a visual indicator display disposed to the rear of the substrate. The visual indicator display may be part of a blind spot detection and display system of the vehicle wherein the visual indicator display is actuated to emit light responsive to a detection by a blind spot detection detector of the equipped vehicle of an overtaking vehicle in a side lane adjacent the side of the equipped vehicle. The visual indicator display includes at least a first indicator at a first location to the rear of the exterior reflective mirror element. A first portion of the reflector may be at least partially removed at the first location in order to establish an at least partially transmissive first portion of the exterior reflective mirror element at the first location.