dimethyl 4-[trans-4'-(N,N-dimethylamino)-styryl]pyridine-2,6-dicarboxylate | 1146950-84-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: dimethyl 4-[trans-4'-(N,N-dimethylamino)-styryl]pyridine-2,6-dicarboxylate
• 英文别名: trans-dimethyl 4-(4'-(dimethylamino)styryl)pyridine-2,6-dicarboxylate；dimethyl 4-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]pyridine-2,6-dicarboxylate
• CAS: 1146950-84-6
• 化学式: C₁₉H₂₀N₂O₄
• 分子量: 340.379
• InChiKey: NDWOWCSAJGWTLQ-AATRIKPKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  68.7
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  dimethyl 4-[trans-4'-(N,N-dimethylamino)-styryl]pyridine-2,6-dicarboxylate 在 水 、 sodium hydroxide 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 生成
  参考文献：
  名称：

  Eu（III），Tb（III）与含有吡啶-2,6-二羧酸单元的新型配体的配合物：合成，表征，荧光性质及其在生物成像中的应用

  摘要：

  包含吡啶-2,6-二羧酸单元，反式-4-（4'-甲氧基苯乙烯基）吡啶-2,6-二羧酸，反式-4-（4'-（（二甲氨基）苯乙烯基）吡啶-2，合成了6-二羧酸和反式-4-（4'-（二苯基氨基）苯乙烯基）吡啶-2,6-二羧酸，并成功制备了它们与Eu（III），Tb（III）离子的配合物。借助MS，元素分析，IR，1 H NMR和TG-DTA对配体和相应的金属配合物进行了表征。研究了固态的Eu（III）和Tb（III）配合物的发光光谱。可以观察到Eu（III）在615 nm和Tb（III）在545 nm处的强发光峰。研究了and和complex配合物在细胞成像中的应用。

  DOI：

  10.1016/j.saa.2011.09.036
• 作为产物：
  描述：

  dimethyl 4-formylpyridine-2,6-dicarboxylate 、 4-(N,N-dimethylamino)benzyltriphenylphosphonium iodide 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 以45%的产率得到dimethyl 4-[trans-4'-(N,N-dimethylamino)-styryl]pyridine-2,6-dicarboxylate
  参考文献：
  名称：

  Dipicolinate as acceptor in D–π–A chromophores: synthesis, characterization and fluorescence following single- and two-photon excitation

  摘要：

  Three novel donor-pi-acceptor type compounds with dipicolinate as acceptor have been synthesized. Their absorption, photoluminescence as well as their two-photon absorption properties have been investigated. Two of them show strong two-photon absorption and two-photon excited Up-conversion fluorescence. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.09.073

文献信息

• Dipicolinate as acceptor in D–π–A chromophores: synthesis, characterization and fluorescence following single- and two-photon excitation
  作者：Haibo Xiao、Xiaoming Tao、Yaochuan Wang、Shixiong Qian、Guanghao Shi、Hui Li

  DOI：10.1016/j.tetlet.2008.09.073

  日期：2008.11

  Three novel donor-pi-acceptor type compounds with dipicolinate as acceptor have been synthesized. Their absorption, photoluminescence as well as their two-photon absorption properties have been investigated. Two of them show strong two-photon absorption and two-photon excited Up-conversion fluorescence. (C) 2008 Elsevier Ltd. All rights reserved.
• Synthesis of Novel Donor–π–Acceptor Chromophores with Dipicolinate as Acceptor
  作者：Haibo Xiao、Xiaoming Tao、Hui Li、Guanghao Shi

  DOI：10.1080/00397910802531963

  日期：2009.3.25

  Three novel donor--acceptor (D--A) chromophores, with dipicolinate as acceptor, have been synthesized. All the compounds were characterized by 1H NMR, infrared (IR) spectroscopy, mass spectrometry (MS), and elemental analysis.
• Eu(III), Tb(III) complexes with novel ligands containing pyridine-2,6-dicarboxylic acid unit: Synthesis, characterization, fluorescence properties and application in biological imaging
  作者：Haibo Xiao、Minjuan Chen、Chong Mei、Hongyao Yin、Xiaoying Zhang、Xiaoxia Cao

  DOI：10.1016/j.saa.2011.09.036

  日期：2011.12

  novel ligands containing pyridine-2,6-dicarboxylic acid unit, trans-4 -(4′-methoxystyryl) pyridine-2,6-dicarboxylic acid, trans-4-(4′-(dimethylamino)styryl)pyridine-2,6-dicarboxylic acid, and trans-4-(4′-(diphenylamino)styryl)pyridine-2,6-dicarboxylic acid were synthesized and their complexes with Eu(III), Tb(III) ions were successfully prepared. The ligands and the corresponding metal complexes were

  包含吡啶-2,6-二羧酸单元，反式-4-（4'-甲氧基苯乙烯基）吡啶-2,6-二羧酸，反式-4-（4'-（（二甲氨基）苯乙烯基）吡啶-2，合成了6-二羧酸和反式-4-（4'-（二苯基氨基）苯乙烯基）吡啶-2,6-二羧酸，并成功制备了它们与Eu（III），Tb（III）离子的配合物。借助MS，元素分析，IR，1 H NMR和TG-DTA对配体和相应的金属配合物进行了表征。研究了固态的Eu（III）和Tb（III）配合物的发光光谱。可以观察到Eu（III）在615 nm和Tb（III）在545 nm处的强发光峰。研究了and和complex配合物在细胞成像中的应用。