[EN] AN IMPROVED PROCESS FOR THE PREPARATION OF 1-ARYL 2-AMINOMETHYL CYCLOPROPANE CARBOXYAMIDE (Z) DERIVATIVES, THEIR ISOMERS AND SALTS<br/>[FR] PROCÉDÉ PERFECTIONNÉ POUR LA PRÉPARATION DE DÉRIVÉS DE 1-ARYL-2-AMINOMÉTHYLCYCLOPROPANECARBOXAMIDE (Z), DE LEURS ISOMÈRES ET DE LEURS SELS
申请人:MICRO LABS LTD
公开号:WO2014009767A1
公开(公告)日:2014-01-16
The present invention relates to an improved and one-pot process for the preparation of 1-Aryl 2-aminomethyl cyclopropane carboxyamide (z) derivatives, their isomers of formula (I) or its pharmaceutically acceptable salt thereof wherein R1 and R2 are represents independently selected from the group consisting of hydrogen, lower alkyl, lower aryl, and lower-alkylaryl, which aryl or alkylaryl group is optionally substituted by a halogen atom.