18-氟十八烷酸甲酯 | 463-29-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 18-氟十八烷酸甲酯
• 英文名称: methyl 18-fluorostearate
• 英文别名: 18-fluoro-octadecanoic acid methyl ester；18-Fluor-octadecansaeure-methylester；Methyl 18-fluorooctadecanoate
• CAS: 463-29-6
• 化学式: C₁₉H₃₇FO₂
• 分子量: 316.5
• InChiKey: CYLLSGSDEOHZKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8
• 重原子数：
  22
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2915900090

反应信息

• 作为反应物：
  描述：

  18-氟十八烷酸甲酯 在 sodium hydroxide 作用下， 生成 18-氟十八烷酸
  参考文献：
  名称：

  Anodic Syntheses Involving ι-Monohalocarboxylic Acids¹

  摘要：

  DOI：

  10.1021/ja01591a062
• 作为产物：
  描述：

  10-氟癸烷-1-醇 在 chromium(VI) oxide 、 sodium 、 溶剂黄146 作用下， 生成 18-氟十八烷酸甲酯
  参考文献：
  名称：

  Anodic Syntheses Involving ι-Monohalocarboxylic Acids¹

  摘要：

  DOI：

  10.1021/ja01591a062

文献信息

• Omega-Functionalized Fatty Acids, Alcohols, and Ethers via Olefin Metathesis
  作者：Jonathan A. Zerkowski、Daniel K. Y. Solaiman

  DOI：10.1007/s11746-012-2015-0

  日期：——

  AbstractMethyl 17‐hydroxy stearate was converted to methyl octadec‐16‐enoate using copper sulfate adsorbed on silica gel. This compound served as a useful substrate for the olefin metathesis reaction. As a result, several fatty acids with novel functional groups at the ω‐end were prepared: a glyceryl ether attached at the 18‐carbon, an aromatic fatty acid from eugenol, and a ferrocenyl fatty acid. By employing the unsaturated fatty alcohol, other groups were introduced, namely the terminal fluoride, bromide, and iodide were prepared, as was a thiol derivative. The penultimate and omega olefins reported here should serve as building blocks that allow fatty acids to make a greater contribution to a range of emerging technological areas.
• Anodic Syntheses Involving ι-Monohalocarboxylic Acids¹
  作者：F. L. M. Pattison、J. B. Stothers、R. G. Woolford

  DOI：10.1021/ja01591a062

  日期：1956.5