(Z)-三甲基(1-(甲基磺酰基)-2-苯基乙烯基)硅烷 | 185844-50-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (Z)-三甲基(1-(甲基磺酰基)-2-苯基乙烯基)硅烷
• 英文名称: trimethyl-[(Z)-1-methylsulfonyl-2-phenylethenyl]silane
• CAS: 185844-50-2
• 化学式: C₁₂H₁₈O₂SSi
• 分子量: 254.425
• InChiKey: VTIDQXXRCNJNJC-ZRDIBKRKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.95
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (Z)-三甲基(1-(甲基磺酰基)-2-苯基乙烯基)硅烷 在 cesium fluoride 作用下， 以 二甲基亚砜 为溶剂， 生成 (E)-methyl styryl sulfone 、 [(Z)-2-甲基磺酰基乙烯基]苯
  参考文献：
  名称：

  Chemistry of silyl thioketones. Part 10. Synthesis and reactivity of α-silyl vinyl sulfides

  摘要：

  Aliphatic silyl thioketones containing an alpha-hydrogen atom undergo enethiolization to Z-alpha-silyl enethiols 2. Compounds 2 react with a variety of halides R(3)X to give open-chain alpha-silyl vinyl sulfides 3. Protiodesilylation of 3 was achieved upon treatment with fluoride ion to give vinyl sulfides 4. Reaction of 3 with Grignard reagents, in the presence of an appropriate nickel catalyst, results in a series of vinylsilanes 5 with a specific geometry.

  DOI：

  10.1039/p19960002803
• 作为产物：
  描述：

  (phenylacetyl)trimethylsilane 在 盐酸 、 Oxone 、 硫化氢 、 potassium carbonate 作用下， 以 甲醇 、 乙醚 、 丙酮 为溶剂， 反应 4.0h， 生成 (Z)-三甲基(1-(甲基磺酰基)-2-苯基乙烯基)硅烷
  参考文献：
  名称：

  Chemistry of silyl thioketones. Part 10. Synthesis and reactivity of α-silyl vinyl sulfides

  摘要：

  Aliphatic silyl thioketones containing an alpha-hydrogen atom undergo enethiolization to Z-alpha-silyl enethiols 2. Compounds 2 react with a variety of halides R(3)X to give open-chain alpha-silyl vinyl sulfides 3. Protiodesilylation of 3 was achieved upon treatment with fluoride ion to give vinyl sulfides 4. Reaction of 3 with Grignard reagents, in the presence of an appropriate nickel catalyst, results in a series of vinylsilanes 5 with a specific geometry.

  DOI：

  10.1039/p19960002803

文献信息

• Chemistry of silyl thioketones. Part 10. Synthesis and reactivity of α-silyl vinyl sulfides
  作者：Bianca Flavia Bonini、Mauro Comes-Franchini、Mariafrancesca Fochi、Germana Mazzanti、Francesca Peri、Alfredo Ricci

  DOI：10.1039/p19960002803

  日期：——

  Aliphatic silyl thioketones containing an alpha-hydrogen atom undergo enethiolization to Z-alpha-silyl enethiols 2. Compounds 2 react with a variety of halides R(3)X to give open-chain alpha-silyl vinyl sulfides 3. Protiodesilylation of 3 was achieved upon treatment with fluoride ion to give vinyl sulfides 4. Reaction of 3 with Grignard reagents, in the presence of an appropriate nickel catalyst, results in a series of vinylsilanes 5 with a specific geometry.