n-Dotriacontanoic acid methyl ester | 41755-79-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: n-Dotriacontanoic acid methyl ester
• 英文别名: dotriacontanoic acid methyl ester；Methyl n-dotriacontanoate；methyl dotriacontanoate；Dotriacontansaeure-methylester；Hentriacontanol-acetat
• CAS: 41755-79-7
• 化学式: C₃₃H₆₆O₂
• 分子量: 494.886
• InChiKey: MRFBEUTXKBRYNS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.6
• 重原子数：
  35
• 可旋转键数：
  31
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  n-Dotriacontanoic acid methyl ester 在 吡啶 、 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 生成 n-Dotriacontanyl acetate
  参考文献：
  名称：

  Kuwahara, Yasumasa, Agricultural and Biological Chemistry, 1980, vol. 44, # 6, p. 1297 - 1300

  摘要：

  DOI：
• 作为产物：
  描述：

  methyl 8-[2-(5-docosylthiophen-2-yl)-1,3-dithiolan-2-yl]octanoate 在 W₆ Raney nickel 作用下， 以 乙醇 为溶剂， 生成 n-Dotriacontanoic acid methyl ester
  参考文献：
  名称：

  Rao, S. Jagadishwar; Bhalerao, U. T.; Tilak, B. D., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1987, vol. 26, # 1-12, p. 208 - 211

  摘要：

  DOI：

文献信息

• Bioactive Phenylethanoids and Coumarines from Basalmocitrus cameroonensis
  作者：Jean Duplex Wansi、Judith Liliane Djouaka Bavoua、Emmanuel Ngeufa Happi、Krishna Prasad Devkota、Bruno Ndjakou Lenta、Muhammed Ahmed Mesaik、Muhammad Iqbal Choudhary、Zacharias Tanee Fomum、Norbert Sewald

  DOI：10.1515/znb-2009-0417

  日期：2009.4.1

  Two new phenylethanoids, basalethanoid A (1) and B (2), and one new ceramide, basalamide A (3), together with eleven known compounds (4 - 14) were isolated from theMeOH extract of the stem barks of Basalmocitrus cameroonensis. The structures of all compounds were determined by comprehensive analyses of their 1D and 2D NMR, mass spectral (EI and ESI) data, chemical reactions, and comparison with previously known analogs. Compounds 1, 2, 5, and 7 - 10 demonstrated a strong inhibition on reactive oxygen species (ROS) production in the oxidative burst activity of whole blood on activation with serum opsonized zymosan in the range of IC₅₀ = 0.06 - 12.30 μg mL⁻¹.

  两种新的苯乙酸酯类化合物，basalethanoid A（1）和B（2），以及一种新的酰胺类化合物，basalamide A（3），连同从喀麦隆Basalmocitrus树皮甲醇提取物中分离得到的十一个已知化合物（4-14）。所有化合物的结构均通过对它们的1D和2D NMR、质谱（EI和ESI）数据、化学反应以及与先前已知类似物的比较进行全面分析确定。化合物1、2、5和7-10在全血氧化爆发活性中对血清包被的酵母菌活化产生的活性氧自由基（ROS）的抑制作用强烈，IC50范围为0.06-12.30μg mL-1。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• Abubidentin A, New Oleanane-type Triterpene Ester from <i>Abutilon bidentatum</i> and its antioxidant, cholinesterase and antimicrobial activities
  作者：Gadah A. Al-Hamoud、Nawal M. Al-Musayeib、Musarat Amina、Sabrin R.M. Ibrahim

  DOI：10.7717/peerj.13040

  日期：——

  comparison with data reported in the literature. The extract and isolated compounds were evaluated for antioxidant, cholinesterase inhibitory, and antimicrobial activities. Results A new oleanane-type triterpene ester, namely abubidentin A (3) (α, 3β, 30-trihydroxy-29-carboxy-olean-9(11), 12-diene-3-dotriacontanoate), along with two known compounds: 2-hydroxydocosanoic acid (1) and stigmasta-22-ene-3-β-ol (2)

  背景 这项工作描述了 Abutilon bidentatum Hochst 地上部分的植物化学和生物学研究。沙特原产地。方法 A. bidentatum 的乙醇提取物的石油醚级分在硅胶柱上分馏，并使用不同的色谱程序进一步纯化以分离化合物。所有纯分离化合物的化学结构均通过使用 IR、UV、1H、13C NMR 和 MS 光谱和化学方法（碱水解）解释其光谱数据以及与文献中报道的数据进行比较来阐明。对提取物和分离化合物的抗氧化、胆碱酯酶抑制和抗菌活性进行了评估。结果 一种新的齐墩果烷型三萜酯，即abubidentin A (3) (α, 3β, 30-trihydroxy-29-carboxy-olean-9(11​​), 12-diene-3-dotriacontanoate)，以及两种已知化合物：2-hydroxydocosanoic acid (1) 和 stigmasta-22-ene-3-β-ol
• FUKUSHIMA, KAZUO;ISHIWATARI, RYOSHI, J. ANAL. AND APPL. PYROL., 11,(1987) 109-124
  作者：FUKUSHIMA, KAZUO、ISHIWATARI, RYOSHI

  DOI：——

  日期：——