3,4-Dihydro-5,8-dimethylisochinolin | 855649-25-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢异喹啉
• 英文名称: 3,4-Dihydro-5,8-dimethylisochinolin
• 英文别名: 5,8-dimethyl-3,4-dihydro-isoquinoline；5,8-Dimethyl-3,4-dihydro-isochinolin；5,8-Dimethyl-3,4-dihydroisoquinoline
• CAS: 855649-25-1
• 化学式: C₁₁H₁₃N
• 分子量: 159.231
• InChiKey: IBHJWDPKHXVCAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,4-Dihydro-5,8-dimethylisochinolin 在 palladium on activated charcoal 作用下， 生成 5,8-dimethylisoquinoline
  参考文献：
  名称：

  Hormonal control of a gene encoding a putative PDR5-like ABC transporter in periwinkle

  摘要：

  ATP binding cassette (ABC) transporters retain increasing attention since their implication in multidrug resistance has been demonstrated in several prokaryotic and eukaryotic cells. Many ARC proteins are known in various organisms but only few in higher plants. We report here on the characterization of a partial 955 bp clone (Cr-ABC1) isolated from a Catharanthus roseus cDNA library, which shows high homology (65% identity) with the TUR2 cDNA previously isolated from the water lens Spirodela polyrrhiza. Accumulation of Cr-ABC1 transcripts in cultured C. roseus cells was enhanced by cytokinin or methyl jasmonate addition to, or auxin suppression from the culture medium. In whole plants, the gene was mainly expressed in flowers.

  DOI：

  10.1080/12538078.2000.10515842
• 作为产物：
  描述：

  2,5-二甲基苯胺(请核实!) 在 甲酸 作用下， 生成 3,4-Dihydro-5,8-dimethylisochinolin
  参考文献：
  名称：

  Hormonal control of a gene encoding a putative PDR5-like ABC transporter in periwinkle

  摘要：

  ATP binding cassette (ABC) transporters retain increasing attention since their implication in multidrug resistance has been demonstrated in several prokaryotic and eukaryotic cells. Many ARC proteins are known in various organisms but only few in higher plants. We report here on the characterization of a partial 955 bp clone (Cr-ABC1) isolated from a Catharanthus roseus cDNA library, which shows high homology (65% identity) with the TUR2 cDNA previously isolated from the water lens Spirodela polyrrhiza. Accumulation of Cr-ABC1 transcripts in cultured C. roseus cells was enhanced by cytokinin or methyl jasmonate addition to, or auxin suppression from the culture medium. In whole plants, the gene was mainly expressed in flowers.

  DOI：

  10.1080/12538078.2000.10515842

文献信息

• Elektronenstoßinduzierter Verlust der Substituenten an C-5 und C-8 bei 1,2,3,4-Tetrahydroisochinolinen, 4. Mitt. Untersuchungen zum Mechanismus
  作者：Klaus K. Mayer、Georg Stöber、Wolfgang Wiegrebe

  DOI：10.1002/ardp.19843170204

  日期：——

  Beim Elektronenstoß‐induzierten Zerfall der in Mitt. 1–3 beschriebenen Tetrahydroisochinoline 1–19 werden die Substituenten an C‐5 und C‐8 in einstufiger Reaktion abgespalten. Anwendungsbreite und Mechanismus dieser Fragmentierung werden untersucht.

  在注释 1-3 中描述的四氢异喹啉 1-19 的电子碰撞诱导衰变中，C-5 和 C-8 处的取代基在一步反应中分裂。检查了这种碎片化的范围和机制。
• MAYER, K. K.;STOEBER, G.;WIEGREBE, W., ARCH. PHARM., 1984, 317, N 2, 107-117
  作者：MAYER, K. K.、STOEBER, G.、WIEGREBE, W.

  DOI：——

  日期：——
• ORGANIC LIGHT EMITTING DISPLAY DEVICE
  申请人：LG Display Co., Ltd.

  公开号：EP3082173B1

  公开（公告）日：2018-05-09
• Hormonal control of a gene encoding a putative PDR5-like ABC transporter in periwinkle
  作者：Michel Cannieux、Anne-Marie Droual、Françoise Andreu、Jean-Claude Chénieux、Marc Rideau、Saïd Hamdi

  DOI：10.1080/12538078.2000.10515842

  日期：2000.1

  ATP binding cassette (ABC) transporters retain increasing attention since their implication in multidrug resistance has been demonstrated in several prokaryotic and eukaryotic cells. Many ARC proteins are known in various organisms but only few in higher plants. We report here on the characterization of a partial 955 bp clone (Cr-ABC1) isolated from a Catharanthus roseus cDNA library, which shows high homology (65% identity) with the TUR2 cDNA previously isolated from the water lens Spirodela polyrrhiza. Accumulation of Cr-ABC1 transcripts in cultured C. roseus cells was enhanced by cytokinin or methyl jasmonate addition to, or auxin suppression from the culture medium. In whole plants, the gene was mainly expressed in flowers.