3-(1-phenylbut-3-en-1-yl)-1H-indole | 105949-46-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3-(1-phenylbut-3-en-1-yl)-1H-indole
• 英文别名: 3-(1-phenyl-3-butenyl)-1H-indole；3-(1-phenylbut-3-enyl)-1H-indole
• CAS: 105949-46-0
• 化学式: C₁₈H₁₇N
• 分子量: 247.34
• InChiKey: JXMCKHIWXNJVGU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  15.8
• 氢给体数：
  1
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-diethylcarbamoyl-3-formylindole 在 sodium hydroxide 、 四氯化锡 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 反应 6.33h， 生成 3-(1-phenylbut-3-en-1-yl)-1H-indole
  参考文献：
  名称：

  Synthesis of 3-substituted indoles via N-acylindolium ions

  摘要：

  DOI：

  10.1016/s0040-4039(00)84397-x

文献信息

• Scandium Triflate-Catalyzed Nucleophilic Additions to Indolylmethyl Meldrum’s Acid Derivatives via a Gramine-Type Fragmentation: Synthesis of Substituted Indolemethanes
  作者：Erin L. Armstrong、Huck K. Grover、Michael A. Kerr

  DOI：10.1021/jo4017524

  日期：2013.10.18

  Treatment of indolylmethyl Meldrum’s acids with catalytic scandium triflate and a variety of nucleophiles results in the nucleophilic displacement of the Meldrum’s acid moiety via a gramine-type fragmentation. The reaction is useful for the generation of heterocyclic compounds of significant molecular complexity.

  用催化性三氟甲磺酸scan和各种亲核试剂处理吲哚甲基甲基麦角菌酸导致麦角糖酸部分通过氨基甲酸酯型断裂发生亲核取代。该反应可用于产生具有显着分子复杂性的杂环化合物。
• COMINS, D. L.;STROUD, E. D., TETRAHEDRON LETT., 1986, 27, N 17, 1869-1872
  作者：COMINS, D. L.、STROUD, E. D.

  DOI：——

  日期：——
• RAPID PRETREATMENT
  申请人：Sweetwater Energy, Inc.

  公开号：EP3230463A1

  公开（公告）日：2017-10-18
• ENGINEERED MICROORGANISMS FOR PRODUCTION OF COMMODITY CHEMICALS AND CELLULAR BIOMASS
  申请人：The Regents of the University of California

  公开号：EP3519567A1

  公开（公告）日：2019-08-07
• [EN] BIOFUEL PRODUCTION<br/>[FR] PRODUCTION DE BIOCARBURANT
  申请人：BIO ARCHITECTURE LAB INC

  公开号：WO2009046370A2

  公开（公告）日：2009-04-09

  Methods, enzymes, recombinant microorganism, and microbial systems are provided for converting polysaccharides, such as those derived from biomass, into suitable monosaccharides or oligosaccharides, as well as for converting suitable monosaccharides or oligosaccharides into commodity chemicals, such as biofuels. Commodity chemicals produced by the methods described herein are also provided. Commodity chemical enriched refinery-produced petroleum products are also provided, as well as methods for producing the same.