tetra-O-methyl-aldehydo-D-arabinose | 94799-67-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: tetra-O-methyl-aldehydo-D-arabinose
• 英文别名: tetra-O-methyl-aldehydo-D-arabinose；D-arabino-2,3,4,5-Tetramethoxy-valeraldehyd；Tetra-O-methyl-D-arabinose
• CAS: 94799-67-4
• 化学式: C₉H₁₈O₅
• 分子量: 206.239
• InChiKey: KUYXLTBNJKMAQW-HLTSFMKQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.12
• 重原子数：
  14.0
• 可旋转键数：
  8.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  53.99
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  penta-O-methyl-D-gluconic acid amide 在 sodium hypochlorite 作用下， 生成 tetra-O-methyl-aldehydo-D-arabinose
  参考文献：
  名称：

  Haworth et al., Journal of the Chemical Society, 1938, p. 1975,1980

  摘要：

  DOI：

文献信息

• Magnetic Resonance Imaging Findings in Patients With Severe Neonatal Indirect Hyperbilirubinemia
  作者：Yüksel Yilmaz、Gülay Alper、Gamze Kiliçoglu、Levent Çelik、Leyla Karadeniz、Serpil Yilmaz-Degirmenci

  DOI：10.1177/088307380101600615

  日期：2001.6

  The aim of this study was to document the magnetic resonance imaging (MRI) findings of cases with a history of severe neonatal indirect hyperbilirubinemia. Ten cases (eight cases with neurologic findings, two normal cases) with a history of severe neonatal indirect hyperbilirubinemia were studied. Neurologic findings and MRI results were described and correlated. Seven of eight cases with neurologic findings demonstrated symmetric and uniform increased T₂ signal changes limited to globus pallidi. MRI scans of two cases without neurologic findings showed no abnormality. Severe neonatal indirect hyperbilirubinemia should be considered in the differential diagnosis of bilateral symmetric hyperintense signal changes in the globus pallidus on MRI. However, high levels of unconjugated bilirubin concentrations in the neonatal period may not always cause such lesions of globus pallidus on MRI despite the presence of neurologic findings. (J Child Neurol 2001;16:452-455).

  本研究的目的是记录具有严重新生儿间接性高胆红素血症病史的磁共振成像（MRI）结果。研究了10例（8例有神经学发现，2例正常）具有严重新生儿间接性高胆红素血症病史的病例。描述并相关神经学发现和MRI结果。8例神经学发现的病例中有7例表现出对称和均匀的T2信号改变，仅限于球后核。两例没有神经学发现的病例的MRI扫描未显示异常。应考虑严重新生儿间接性高胆红素血症在MRI上球后核双侧对称高信号变化的差异诊断中。然而，尽管存在神经学发现，新生儿期高水平的非结合胆红素浓度并不总是会导致球后核的这种病变。 (J Child Neurol 2001;16:452-455)。
• Haworth et al., Journal of the Chemical Society, 1938, p. 1975,1980
  作者：Haworth et al.

  DOI：——

  日期：——