1-N,3-N-bis[[1-(2-hydroxyphenyl)triazol-4-yl]methyl]benzene-1,3-dicarboxamide | 1352170-79-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-N,3-N-bis[[1-(2-hydroxyphenyl)triazol-4-yl]methyl]benzene-1,3-dicarboxamide
• CAS: 1352170-79-6
• 化学式: C₂₆H₂₂N₈O₄
• 分子量: 510.512
• InChiKey: VUWRYWNBXRNZGS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  38
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  160
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1-N,3-N-bis[[1-(2-hydroxyphenyl)triazol-4-yl]methyl]benzene-1,3-dicarboxamide 、 四丁基氟化铵 以 氘代二甲亚砜 、 氘代氯仿 为溶剂， 生成
  参考文献：
  名称：

  Triazole-based chromogenic and non-chromogenic receptors for halides

  摘要：

  We designed and synthesized a series of triazole-based receptors for anion recognition. Our studies demonstrated that an amide-linked triazole unit is a promising moiety for anion recognition. We synthesized various chromogenic and non-chromogenic receptors based on this moiety. Receptor 11 binds very strongly (K = 102,750 M-1) to fluoride. Receptor 18 changes color from faint yellow to orange upon binding to fluoride. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.10.066
• 作为产物：
  描述：

  2-氨基苯酚 在 盐酸 、 copper(l) iodide 、 N,N-二异丙基乙胺 、 sodium nitrite 作用下， 以 水 、 乙腈 为溶剂， 生成 1-N,3-N-bis[[1-(2-hydroxyphenyl)triazol-4-yl]methyl]benzene-1,3-dicarboxamide
  参考文献：
  名称：

  Triazole-based chromogenic and non-chromogenic receptors for halides

  摘要：

  We designed and synthesized a series of triazole-based receptors for anion recognition. Our studies demonstrated that an amide-linked triazole unit is a promising moiety for anion recognition. We synthesized various chromogenic and non-chromogenic receptors based on this moiety. Receptor 11 binds very strongly (K = 102,750 M-1) to fluoride. Receptor 18 changes color from faint yellow to orange upon binding to fluoride. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.10.066

文献信息

• Triazole-based chromogenic and non-chromogenic receptors for halides
  作者：V. Haridas、Srikanta Sahu、P.P. Praveen Kumar

  DOI：10.1016/j.tetlet.2011.10.066

  日期：2011.12

  We designed and synthesized a series of triazole-based receptors for anion recognition. Our studies demonstrated that an amide-linked triazole unit is a promising moiety for anion recognition. We synthesized various chromogenic and non-chromogenic receptors based on this moiety. Receptor 11 binds very strongly (K = 102,750 M-1) to fluoride. Receptor 18 changes color from faint yellow to orange upon binding to fluoride. (C) 2011 Elsevier Ltd. All rights reserved.