diethyl 2-cyclohexene-1,1-dicarboxylate | 122086-31-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: diethyl 2-cyclohexene-1,1-dicarboxylate
• 英文别名: Diethyl cyclohex-2-ene-1,1-dicarboxylate
• CAS: 122086-31-1
• 化学式: C₁₂H₁₈O₄
• 分子量: 226.273
• InChiKey: IILOIPNDUDUSQL-UHFFFAOYSA-N

物化性质

• 沸点：
  264.7±40.0 °C(Predicted)
• 密度：
  1.096±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  diethyl 2-cyclohexene-1,1-dicarboxylate 在 phosphate buffer pH 7.2 、 叠氮磷酸二苯酯 、 三乙胺 作用下， 以 二氯甲烷 、 丙酮 、 苯 为溶剂， 反应 60.0h， 生成 (S)-ethyl 1-benzyloxycarbonylamino-2-cyclohexene-1-isocyanate
  参考文献：
  名称：

  Chemoenzymatic synthesis of an α-substituted serine derivative

  摘要：

  An asymmetric synthesis of an alpha-substituted serine derivative was achieved by employing PLE-catalyzed hydrolysis of a prochiral malonate derivative, and the absolute configuration of the hydrolyzed product was unambiguously determined by the X-ray analysis of a camphorsulfonic acid derivative. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00270-0
• 作为产物：
  描述：

  2,2-dicarboethoxycyclohexanone 在 吡啶 、 sodium tetrahydroborate 、 三氟甲磺酸酐 作用下， 以 甲醇 为溶剂， 反应 25.0h， 生成 diethyl 2-cyclohexene-1,1-dicarboxylate
  参考文献：
  名称：

  Chemoenzymatic synthesis of an α-substituted serine derivative

  摘要：

  An asymmetric synthesis of an alpha-substituted serine derivative was achieved by employing PLE-catalyzed hydrolysis of a prochiral malonate derivative, and the absolute configuration of the hydrolyzed product was unambiguously determined by the X-ray analysis of a camphorsulfonic acid derivative. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00270-0

文献信息

• An Intermolecular Azidoheteroarylation of Simple Alkenes via Free-Radical Multicomponent Cascade Reactions
  作者：Zhi Liu、Zhong-Quan Liu

  DOI：10.1021/acs.orglett.7b02788

  日期：2017.10.20

  Based upon a radical polar effect, an intermolecular azidoheteroarylation of simple alkenes via a metal-free radical multicomponent cascade process was achieved. It allows a mild, rapid, and step-economic access to a broad range of azidoalkylated heteroaromatics. Given the diversity in transformations of organic azides and medicinally privileged scaffolds of heteroarenes, this strategy enables efficient

  基于自由基极性效应，通过金属-自由基的多组分级联过程实现了简单烯烃的分子间叠氮杂芳基化。它允许温和，快速，经济地进入各种叠氮烷基化杂芳族化合物。鉴于有机叠氮化物和杂芳烃的药用特权支架的转化多样性，该策略可实现药物和候选物的高效合成和后期衍生化。
• Oxidative deprotonation of carbonyl compounds by Fe(III) salts
  作者：Attilio Citterio、Anna Cerati、Roberto Sebastiano、Claudia Finzi、Roberto Santi

  DOI：10.1016/s0040-4039(00)72739-0

  日期：1989.1

  Iron (III) salts (perchlorate and nitrate nonahydrate) in acetonitrile or acetic anhydride at 0–50°C oxidize the ∝-position of malonic esters efficiently via the corresponding radicals. In the presence of olefins and aromatics, inter- and intramolecular free radical chain or oxidative additions are observed.

  乙腈或乙酸酐中的铁（III）盐（高氯酸盐和硝酸盐九水合物）在0–50°C下可通过相应的自由基有效氧化丙二酸酯的α-位。在烯烃和芳族化合物的存在下，观察到分子间和分子内的自由基链或氧化加成。
• HETEROPHASIC PROPYLENE POLYMERIC MATERIAL
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP3495420A1

  公开（公告）日：2019-06-12

  A heterophasic propylene polymerization material comprising a propylene homopolymer component or a specific propylene copolymer component, and a specific ethylene-α-olefin copolymer component, in which (i) the amount of the xylene-soluble component is 40% by weight or more, (ii) the limiting viscosity [η]CXIS of the xylene-insoluble component is 1.50 dL/g or more, (iii) the ratio of the limiting viscosity [η]CXS of the xylene-soluble component to the limiting viscosity [η]CXIS of the xylene-insoluble component is 1.5 or less, and (iv) the content of monomer units derived from ethylene and α-olefins having 4 to 12 carbon atoms in the xylene-insoluble component is 6% by weight or more.

  一种异相丙烯聚合材料，包括丙烯均聚物组分或特定丙烯共聚物组分，以及特定乙烯-α-烯烃共聚物组分，其中(i)二甲苯可溶组分的量为40%（重量）或以上，(ii)二甲苯不溶组分的极限粘度[η]CXIS为1.(iii) 二甲苯可溶组分的极限粘度[η]CXS 与二甲苯不溶组分的极限粘度[η]CXIS 之比为 1.5 或以下，以及 (iv) 二甲苯不溶组分中来自乙烯和具有 4 至 12 个碳原子的 α-烯烃的单体单元的含量为 6%（重量比）或以上。
• THERMOPLASTIC ELASTOMER COMPOSITION AND METHOD OF PRODUCING THE SAME
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP3744784A1

  公开（公告）日：2020-12-02

  There is provided a thermoplastic elastomer composition from which a molded article having an appearance suitable for non-painting use can be produced. In the thermoplastic elastomer composition containing at least two olefin polymers, a content of an insoluble component in ortho-dichlorobenzene at 140°C is 20 wt% to 50 wt% and an isothermal crystallization time measured at 130°C is 300 seconds or longer.

  本发明提供了一种热塑性弹性体组合物，用该组合物可以生产出外观适用于非涂漆用途的模塑制品。在含有至少两种烯烃聚合物的热塑性弹性体组合物中，140°C 时邻二氯苯中的不溶组分含量为 20 wt% 至 50 wt%，130°C 时的等温结晶时间为 300 秒或更长。
• HETEROPHASIC PROPYLENE POLYMER MATERIAL AND USE OF THE SAME
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP3842489A1

  公开（公告）日：2021-06-30

  Provided is a heterophasic propylene polymer material having excellent low temperature impact resistance, tensile strength, and tensile elongation. A heterophasic propylene polymer material contains a propylene homopolymer component (A), and an ethylene-propylene copolymer component (B1) and an ethylene-propylene copolymer component (B2) having different formulations from each other, wherein a content of the propylene homopolymer component (A), a content of the ethylene-propylene copolymer component (B1), and a content of the ethylene-propylene copolymer component (B2) are 40 to 70 parts by mass, 15 to 54 parts by mass, and 6 to 15 parts by mass, respectively, with respect to 100 parts by mass of a total content of the propylene homopolymer component (A) and the ethylene-propylene copolymer components (B1) and (B2).

  本发明提供了一种杂相丙烯聚合物材料，它具有优异的低温抗冲击性、拉伸强度和拉伸伸长率。一种杂相丙烯聚合物材料包含丙烯均聚物组分（A）、乙烯-丙烯共聚物组分（B1）和乙烯-丙烯共聚物组分（B2），它们的配方互不相同，其中丙烯均聚物组分（A）的含量、乙烯-丙烯共聚物组分（B1）的含量、乙烯-丙烯共聚物组分（B2）的含量和乙烯-丙烯共聚物组分（B1）的含量都不同、和乙烯-丙烯共聚物组分（B2）的含量，相对于丙烯均聚物组分（A）和乙烯-丙烯共聚物组分（B1）和（B2）总含量的 100 重量份，分别为 40 至 70 重量份、15 至 54 重量份和 6 至 15 重量份。