| 160855-23-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 160855-23-2
• 化学式: C₆H₄O₂S
• 分子量: 140.163
• InChiKey: OXIPUGRKFLQPKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.94
• 重原子数：
  9.0
• 可旋转键数：
  0.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  4-甲氧基苯乙烯 、 生成 2,3-dihydro-2-(4-metoxy-phenyl)-1,4-benzoxathiin-7-ol
  参考文献：
  名称：

  Antimycotic activity of 4-thioisosteres of flavonoids towards yeast and yeast-like microorganisms

  摘要：

  Different substituted methoxy- and hydroxy-4-thioisosteres of flavonoids were prepared and their in vitro antimycotic activity towards yeast (Candida spp., Clavispora spp., Cryptococcus spp., Filobasidiella spp., Issatchenkia spp., Pichia spp., Kluyveromyces spp., Saccharomyces spp. and Yarrowia spp.) and yeast-like (Prototheca spp.) microorganisms was tested. Further insights in the biological activities of these antioxidant, oestrogenic and antimicrobial biomimetic derivatives were obtained. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2008.05.048