N-dimesitylchlorogermyl-3-amino-2-methyl thiophoate | 135302-94-2

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: N-dimesitylchlorogermyl-3-amino-2-methyl thiophoate
• 英文别名: methyl 3-[[chloro-bis(2,4,6-trimethylphenyl)germyl]amino]thiophene-2-carboxylate
• CAS: 135302-94-2
• 化学式: C₂₄H₂₈ClGeNO₂S
• 分子量: 502.601
• InChiKey: JCPMPNQYMIRBNV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.29
• 重原子数：
  30.0
• 可旋转键数：
  5.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  38.33
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  N-dimesitylchlorogermyl-3-amino-2-methyl thiophoate 在 叔丁基锂 作用下， 以 四氢呋喃 、 苯 为溶剂， 以93%的产率得到methyl 3-[bis(2,4,6-trimethylphenyl)germylideneamino]thiophene-2-carboxylate
  参考文献：
  名称：

  Sur la stabilisation d'une germa-imine par effet stérique et mésomérie

  摘要：

  Delithiochloration of N-lithio-N-dimesitylchlorogermyl-3-amino-2-methyl-thiophoate at low temperature leads to the corresponding germa-imine, stabilized by the steric effects of mesityl substituents linked to germanium and possibly by mesomeric effects with the thiophoate group. This germa-imine, stable at room temperature was characterized by spectrometry (IR, UV, RMN, DCi mass spectrometry). With specific reagents (MeOH, Et3NH+Cl-, etc.) the reactivity is different from that of cyclodiger-mazanes, dimers of germa-imines; stoichiometric addition of MeOH and HCl without cleavage of germanium-nitrogen bond is observed. 3,5-Di-t-butylorthoquinone leads to the expected germadiox-olane, through decomposition of the transient 1,4-cycloadduct observed in H-1 NMR.

  DOI：

  10.1016/0022-328x(92)83281-l
• 作为产物：
  描述：

  methyl 3-[bis(2,4,6-trimethylphenyl)germylideneamino]thiophene-2-carboxylate 在 三乙胺盐酸盐 作用下， 以 苯 为溶剂， 以57%的产率得到N-dimesitylchlorogermyl-3-amino-2-methyl thiophoate
  参考文献：
  名称：

  Sur la stabilisation d'une germa-imine par effet stérique et mésomérie

  摘要：

  Delithiochloration of N-lithio-N-dimesitylchlorogermyl-3-amino-2-methyl-thiophoate at low temperature leads to the corresponding germa-imine, stabilized by the steric effects of mesityl substituents linked to germanium and possibly by mesomeric effects with the thiophoate group. This germa-imine, stable at room temperature was characterized by spectrometry (IR, UV, RMN, DCi mass spectrometry). With specific reagents (MeOH, Et3NH+Cl-, etc.) the reactivity is different from that of cyclodiger-mazanes, dimers of germa-imines; stoichiometric addition of MeOH and HCl without cleavage of germanium-nitrogen bond is observed. 3,5-Di-t-butylorthoquinone leads to the expected germadiox-olane, through decomposition of the transient 1,4-cycloadduct observed in H-1 NMR.

  DOI：

  10.1016/0022-328x(92)83281-l

文献信息

• RIVIERE-BAUDET, M.;RIVIERE, P.;CASTEL, A.;MORERE, A.;ABDENNHADER, C., J. ORGANOMET. CHEM., 409,(1991) N-2, C. 131-141
  作者：RIVIERE-BAUDET, M.、RIVIERE, P.、CASTEL, A.、MORERE, A.、ABDENNHADER, C.

  DOI：——

  日期：——