methyl 3-[[[(2-methoxycarbonylthiophen-3-yl)amino]-bis(2,4,6-trimethylphenyl)germyl]amino]thiophene-2-carboxylate | 135302-95-3

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: methyl 3-[[[(2-methoxycarbonylthiophen-3-yl)amino]-bis(2,4,6-trimethylphenyl)germyl]amino]thiophene-2-carboxylate
• CAS: 135302-95-3
• 化学式: C₃₀H₃₄GeN₂O₄S₂
• 分子量: 623.333
• InChiKey: RPVHKTMGWWRLLQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.01
• 重原子数：
  39.0
• 可旋转键数：
  8.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  76.66
• 氢给体数：
  2.0
• 氢受体数：
  8.0

反应信息

• 作为产物：
  描述：

  、 以 四氢呋喃 、 苯 为溶剂， 以88%的产率得到methyl 3-[[[(2-methoxycarbonylthiophen-3-yl)amino]-bis(2,4,6-trimethylphenyl)germyl]amino]thiophene-2-carboxylate
  参考文献：
  名称：

  Obtention d'organochlorogermylamines stabilisées par un substituant organique chelatant: le 3-amino 2-methylthiophoate

  摘要：

  The use of 3-amino 2-methylthiophoate allows the formation of stabilized organohalogermylamines. 3-Organochlorogermylamino 2-methylthiophoates were synthesized either by intermolecular dehydrochlorination between chlorogermanes and the amino-thiophoate in the presence of DBU or by reaction of chlorogermanes with the coresponding thiophoate lithium amide. A probable complexation between the carbonyl group of the ester function with the electrophilic germanium center is supported by spectroscopic data (IR, UV, temperature H-1 NMR) and can explain the enhanced reactivity of the Ge-Cl bond which allows easy synthesis of sterically hindered bis(3-amino-2-methyl thiophoates)-diorganogermanes.

  DOI：

  10.1016/0022-328x(91)86138-g

文献信息

• RIVIERE-BAUDET, M.;RIVIERE, P.;CASTEL, A.;MORERE, A.;ABDENNHADER, C., J. ORGANOMET. CHEM., 409,(1991) N-2, C. 131-141
  作者：RIVIERE-BAUDET, M.、RIVIERE, P.、CASTEL, A.、MORERE, A.、ABDENNHADER, C.

  DOI：——

  日期：——