4-methylphenyl 4’-methoxyphenyl telluride | 65365-76-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-methylphenyl 4’-methoxyphenyl telluride
• 英文别名: 4-methylphenyl(4-methoxyphenyl)telluride；1-methoxy-4-(phenyltelluro)benzene；4-tolyl-4-methoxylphenyl-telluride；(4-methoxyphenyl)(p-tolyl)tellane；p-methoxyphenyl-p-tolyl-telluride；p-Methoxyphenyl-p-tolyltellurid；1-Methoxy-4-[(4-methylphenyl)tellanyl]benzene；1-methoxy-4-(4-methylphenyl)tellanylbenzene
• CAS: 65365-76-6
• 化学式: C₁₄H₁₄OTe
• 分子量: 325.865
• InChiKey: WFIDJKOFZBGIKJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.66
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-methylphenyl 4’-methoxyphenyl telluride 、 丙烯酸乙酯 在 silver(I) acetate 、 三乙胺 、 palladium dichloride 作用下， 以 甲醇 为溶剂， 反应 8.0h， 以49%的产率得到对甲氧基肉桂酸乙酯
  参考文献：
  名称：

  Synthesis of α,β-unsaturated aryl esters via Heck reaction of unsymmetrical aryl tellurides

  摘要：

  A variety of alpha,beta-unsaturated aryl esters were prepared by the direct reaction of unsymmetrical aryltellurides and ethyl acrylate, catalyzed by PdCl2 via a Heck cross-coupling reaction. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.092
• 作为产物：
  描述：

  4-碘甲苯 在 copper(I) oxide 、 碲化氢 、 乙二胺 、 potassium hydroxide 作用下， 以 二甲基亚砜 为溶剂， 反应 30.0h， 生成 4-methylphenyl 4’-methoxyphenyl telluride
  参考文献：
  名称：

  Copper-catalyzed one-pot tandem synthesis of unsymmetrical diaryl chalcogenides from two different aryl iodides

  摘要：

  Unsymmetrical diaryl chalcogenides were synthesized by a novel one-pot tandem process from two different aryl iodides. A symmetrical diaryl dichalcogenide (ArEEAr, E = Se or Te) was initially obtained by a Cu2O-cataylzed coupling reaction of An with elemental selenium or tellurium in the presence of KOH. Without purification, it was subsequently coupled with a different aryl iodide (Ar'I) to give the unsymmetrical diaryl chalcogenides (ArEAr') in good yields. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2015.11.062

文献信息

• Synthesis of Unsymmetrical Diorganyl Chalcogenides under Greener Conditions: Use of an Iodine/DMSO System, Solvent- and Metal-Free Approach
  作者：Sumbal Saba、Jamal Rafique、Antonio L. Braga

  DOI：10.1002/adsc.201500024

  日期：2015.5.4

  Herein, we report a greener iodine‐catalyzed protocol to access different types of unsymmetrical diorganyl chalcogenides. This new approach works in the absence of solvent and metal. The desired products were obtained in good to excellent yields using one equivalent of arylboronic acids, half an equivalent of various diorganyl dichalcogenides, iodine (10 mol%) as a catalyst and 2 equivalents of dimethyl

  本文中，我们报告了一种绿色的碘催化方案，可用于访问不同类型的不对称二有机基硫属元素化物。这种新方法可以在没有溶剂和金属的情况下使用。使用一当量的芳基硼酸，一半当量的各种二有机基二卤代二硫化物，碘（10摩尔％）作为催化剂和2当量的二甲基亚砜（DMSO；作为氧化剂），以良好的产率获得所需的产物。在微波照射下10分钟的时间。
• Synthesis of symmetrical and unsymmetrical tellurides <i>via</i> silver catalysis
  作者：Bruna Goldani、Manoela do Sacramento、Eder J. Lenardão、Ricardo F. Schumacher、Thiago Barcellos、Diego Alves

  DOI：10.1039/c8nj01998c

  日期：——

  cross-coupling reaction of diaryl ditellurides with aryl boronic acids catalyzed by AgNO3. The general applicability and wide substrate scope make this an interesting method for the synthesis of a series of symmetrical and unsymmetrical diaryl tellurides. This silver-catalyzed protocol tolerates a variety of diaryl ditellurides as well as aryl boronic acids by using only 10 mol% of AgNO3 to provide the desired

  我们在这里描述了一种简单有效的方法，用于二芳基二碲化物与AgNO 3催化的芳基硼酸的交叉偶联反应。通用性和广泛的底物范围使该方法成为合成一系列对称和不对称二芳基碲化物的有趣方法。该银催化的方案通过仅使用10 mol％的AgNO 3来耐受多种二芳基二碲化物和芳基硼​​酸，从而以高收率提供所需的产物。通过高分辨率质谱分析提出了该反应机理，并可以检测出活性的（PhTe）2 Ag III中间体。
• Alternative Metal-Free Synthesis of Diorganoyl Selenides and Tellurides Mediated by Oxone®
  作者：Gelson Perin、Diego Alves、Luis Duarte、José Neto、Márcio Silva

  DOI：10.1055/s-0036-1591992

  日期：2018.7

  We herein describe an alternative metal-free methodology for the synthesis of diorganyl selenides and tellurides mediated by ­Oxone®. The products were obtained in moderate to excellent yields by reactions of diorganyl diselenides or ditellurides with aryl boronic acids mediated by Oxone® with use of EtOH as the solvent. The methodology is applicable to a broad scope of diorganyl dichalcogenides and

  我们在此描述了一种替代的无金属方法，用于合成由 Oxone® 介导的二有机硒化物和碲化物。通过二有机基二硒化物或二碲化物与芳基硼酸的反应，以乙醇为溶剂，由 Oxone® 介导，以中等至极好的收率获得产物。该方法适用于广泛的二有机二硫属元素化物和芳基硼​​酸，它们含有富电子、缺电子和空间位阻取代基。
• Bis(p-methoxyphenyl) telluroxide: a new, mild oxidising agent
  作者：Derek H. R. Barton、Steven V. Ley、Clive A. Meerholz

  DOI：10.1039/c39790000755

  日期：——

  Bis(p-methoxyphenyl) telluroxide is a mild and highly selective oxidising reagent for the conversion of thiocarbonyl groups into their oxo analogues and thiols into disulphides, and for the oxidation of a limited number of nitrogeneous compounds although many other easily oxidised functions are not affected.

  双（对甲氧基苯基）碲化物是一种温和的，高度选择性的氧化剂，可将硫代羰基转化为它们的羰基类似物，将硫醇转化为二硫化物，并用于氧化有限数量的含氮化合物，尽管许多其他易氧化的功能均不受影响。
• C–Te Cross-Coupling of Diaryl Ditellurides with Arylboronic Acids by Using Copper(I) Thiophene-2-carboxylate under Mild Conditions
  作者：Shinichi Koguchi、Yuga Shibuya、Yusuke Igarashi、Haruka Takemura

  DOI：10.1055/s-0037-1610324

  日期：2019.1

  arylboronic acids by using copper(I) thiophene-2-carboxylate (CuTC) under mild conditions. Although other studies have reported that highly polar solvents (such as DMSO) or bases are required, this reaction was completed by using CuTC and common solvents under neutral conditions at room temperature. This cross-coupling reaction was performed with diaryl ditellurides and arylboronic acids bearing various

  我们描述了二芳基二碲化物与芳基硼酸的成功交叉偶联，在温和条件下使用铜 (I) 噻吩-2-羧酸 (CuTC)。尽管其他研究报告需要使用高极性溶剂（如 DMSO）或碱，但该反应是在室温中性条件下使用 CuTC 和普通溶剂完成的。这种交叉偶联反应是用二芳基二碲化物和带有各种基团的芳基硼酸进行的，得到相应的二芳基碲化物，产率很好。