Eight Schiff base compounds were prepared by condensation of 1-amino-2-propanol with different benzaldehydes in water. One of the Schiff bases, (z)-N-bezylidene-2-hydroxypropane-1-amine (HL1), was used as a bidentate ligand for preparation of a zirconium complex (Zr(L1)2Cl2). The complex has been used as a catalyst for efficient synthesis of wide variety of indole derivatives in EtOH under mild conditions. The turnover number and reusability of the catalyst indicate that it has high efficiency and is fairly stable under the reaction conditions.
八种席夫碱化合物通过1-
氨基-2-
丙醇与不同
苯甲醛在
水中的缩合反应制备而成。其中一种席夫碱,即(z)-N-苄叉-2-羟基丙-1-胺(HL1),被用作双齿
配体来制备
锆配合物(Zr(L1)2Cl2)。该配合物在温和条件下作为催化剂,在
乙醇中高效合成各种
吲哚衍
生物。催化剂的转化数和可重复使用性表明其在反应条件下具有高效率且相当稳定。