11-氨基十二烷酸 | 7450-67-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 11-氨基十二烷酸
• 英文名称: 11-amino-dodecanoic acid
• 英文别名: 11-Amino-dodecansaeure；11-Amino-laurinsaeure；11-Aminododecanoic acid
• CAS: 7450-67-1
• 化学式: C₁₂H₂₅NO₂
• 分子量: 215.336
• InChiKey: ZDVRPQIPVMARSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  6-thiophen-2-yl-hexanoic acid methyl ester 在 ammonium hydroxide 、 sodium hydroxide 、 盐酸羟胺 、 四氯化锡 、 镍 作用下， 生成 11-氨基十二烷酸
  参考文献：
  名称：

  Gol'dfarb; Kirmalowa, Zhurnal Obshchei Khimii, 1959, vol. 29, p. 897,903; engl. Ausg. S. 881, 885

  摘要：

  DOI：

文献信息

• Thiophene and its homologues as starting compounds for the preparation of aliphatic amino acids
  作者：Ya.L. Gol'dfarb、B.P. Fabrichnyǐ、I.F. Shalavina

  DOI：10.1016/0040-4020(62)80020-9

  日期：1962.1

  A method for the preparation of aliphatic amino acids from thiophene and its homologues has been developed.

  已经开发了一种由噻吩及其同系物制备脂族氨基酸的方法。
• [EN] DRUG CONJUGATES<br/>[FR] CONJUGUÉS DE MÉDICAMENT
  申请人：UNIV MISSOURI

  公开号：WO2009158633A1

  公开（公告）日：2009-12-30

  Conjugated compounds comprising a therapeutic or diagnostic agent linked to a substrate for a cell membrane transporter or receptor by lipophilic linker are provided.

  提供了包含治疗或诊断药物与细胞膜转运体或受体的底物通过亲脂性连接剂连接的共轭化合物。
• An active energy ray curable composition comprised of a maleimide derivative and a method for curing the said curable composition
  申请人：DAINIPPON INK AND CHEMICALS, INC.

  公开号：EP0878482A1

  公开（公告）日：1998-11-18

  Objects of the present invention are the provision of an active energy ray curable composition which can be cured in the absence of a photoinitiator, and which can also be cured at practical light intensities and irradiating energy, and a method for curing the said curable composition; in which the composition comprises a maleimide derivative represented by formula (1): wherein m and n each represent an integer of 1 to 5, and the total of m and n is 6 or smaller, R11 and R12 each represent a linking group selected from the group consisting of ① an alkylene group, ② an alicyclic group, ③ an arylalkylene group, and ④ a cycloalkylalkyene group, G1 and G2 each represent an ester linkage selected from the group consisting of -COO- and - OCO-, R2 represents a linking chain having an average molecular weight of 100 to 100,000 selected from the group consisting of (A) a (poly)ether linking chain and (B) a (poly)ester linking chain, in which at least one organic group selected from the group consisting of ① a straight chain alkylene group, ② a branched alkylene group, ③ an alkylene group having a hydroxyl group, ④ an alicyclic group, ⑤ an aryl group, and ⑥ an arylalkylene group is connected via at least one linkage selected from the group consisting of (a) an ether linkage and (b) an ester linkage.

  本发明的目的是提供一种在没有光引发剂的情况下也能固化，并能在实际光强度和辐照能量下固化的活性能量射线固化组合物，以及固化上述固化组合物的方法；其中，该组合物包括由式（1）表示的马来酰亚胺衍生物： 其中 m 和 n 分别代表 1 至 5 的整数，且 m 和 n 的总和为 6 或更小、 R11 和 R12 各代表一个连接基团，该连接基团选自①亚烷基、②脂环基、③芳基亚烷基和④环烷基炔基、 G1 和 G2 分别代表选自 -COO- 和 -OCO- 组成的组的酯连接、 R2 代表平均分子量为 100 至 100,000 的连接链，选自由 (A) (多)醚连接链和 (B) (多)酯连接链组成的组，其中至少有一个有机基团选自由以下组成的组 ① 直链亚烷基、支链亚烷基、③具有羟基的亚烷基、④脂环族基团、⑤芳基和⑥芳烷基，其中至少一个有机基团通过选自 (a) 醚键和 (b) 酯键的一种连接方式连接。
• Water compatible energy curable compositions containing maleimide derivatives
  申请人：Sun Chemical Corporation

  公开号：EP1666504A1

  公开（公告）日：2006-06-07

  Active water compatible energy curable compositions comprised of maleimide derivatives, water compatible resins and water which are capable of curing at a practical intensity and energy level and a method for curing same.

  由马来酰亚胺衍生物、水相容性树脂和水组成的活性水相容性能量固化组合物，能以实用的强度和能量水平固化，以及固化方法。
• Gear for an electric power steering device the gear comprising a polyamide composition
  申请人：E. I. du Pont de Nemours and Company

  公开号：EP2371903A2

  公开（公告）日：2011-10-05

  A gear for an electric power steering device comprising a polyamide resin composition comprising an impact modifier, polycarbodiimide, and optionally, a phenol-formaldehyde resin that is used for reducing the rotation speed and augmenting the power output of an electric motor in an electric power steering device for an automobile.

  一种用于电动助力转向装置的齿轮，包含一种聚酰胺树脂组合物，该组合物由抗冲改性剂、聚碳化二亚胺和可选的苯酚-甲醛树脂组成，用于降低汽车电动助力转向装置中电动马达的旋转速度并增强其动力输出。