methyl 2-acetoxy 4-methyl pentanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl 2-acetoxy 4-methyl pentanoate
• 英文别名: Methyl 2-acetyloxy-4-methylpentanoate
• 化学式: C₉H₁₆O₄
• 分子量: 188.224
• InChiKey: NVOJXKTYTSSIFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  methyl 2-acetoxy 4-methyl pentanoate 在 C₂₄H₃₂FeN₆⁽²⁺⁾*2F₆Sb^(1-) 、 双氧水 、 溶剂黄146 作用下， 以 水 、 乙腈 为溶剂， 反应 16.2h， 生成 [(3S)-5,5-dimethyl-2-oxooxolan-3-yl] acetate 、 (R)-5,5-dimethyl-2-oxotetrahydrofuran-3-yl acetate
  参考文献：
  名称：

  Directed Metal (Oxo) Aliphatic C–H Hydroxylations: Overriding Substrate Bias

  摘要：

  The first general strategy for a directing effect on metal (oxo)-promoted C-H hydroxylations is described. Carboxylic acid moieties on the substrate overcome unfavorable electronic, steric, and stereoelectronic biases in C-H hydroxylations catalyzed by the non-heme iron complex Fe(PDP). In a demonstration of the power of this directing effect, C-H oxidation is diverted away from an electronically favored C-1 H abstraction/rearrangement pathway in the paclitaxel framework to enable installation of C-2 oxidation in the naturally occurring oxidation state and stereoconfiguration.

  DOI：

  10.1021/ja301685r
• 作为产物：
  描述：

  2-羟基-4-甲基戊酸甲酯 、 乙酸酐 生成 methyl 2-acetoxy 4-methyl pentanoate
  参考文献：
  名称：

  Kodama, vol. 41, p. 970

  摘要：

  DOI：

文献信息

• Pattern forming method, composition kit and resist film, manufacturing method of electronic device using these, and electronic device
  申请人：FUJIFILM Corporation

  公开号：US10031419B2

  公开（公告）日：2018-07-24

  There is provided a pattern forming method comprising (i) forming a film on a substrate using an actinic ray-sensitive or radiation-sensitive resin composition which contains (A) a resin which decomposes due to an action of an acid to change its solubility with respect to a developer and (C) a specific resin, (ii) forming a top coat layer using a top coat composition which contains a resin (T) on the film, (iii) exposing the film which has the top coat layer to actinic rays or radiation, and (iv) forming a pattern by developing the film which has the top coat layer after the exposing.

  本发明提供了一种图案形成方法，包括(i)使用感光树脂组合物或辐射敏感树脂组合物在基底上形成胶片，该组合物包含(A)由于酸的作用而分解，从而改变其相对于显影剂的溶解度的树脂和(C)特定树脂、(ii) 使用含有树脂 (T) 的表层组合物在胶片上形成表层，(iii) 将具有表层的胶片暴露于放 射线或辐射，(iv) 在暴露后对具有表层的胶片进行显影，形成图案。
• Conversion of Esters to 2-Acetoxy Esters via 2-Nosyloxy Esters
  作者：Robert V. Hoffman、Deborah Stoll

  DOI：10.1080/00397919108020815

  日期：1991.1

  Reaction of 2-nosyloxy esters, available in high yields from the reaction of trimethylsilyl ketene acetals with p-((nitrobenzene)sulfonyl) peroxide, with sodium acetate in DMF produces 2-acetoxy ester in good yields.
• Kodama, vol. 41, p. 970
  作者：Kodama

  DOI：——

  日期：——
• Kodama, Journal of Biochemistry, vol. 1, p. 215
  作者：Kodama

  DOI：——

  日期：——
• HOFFMAN, ROBERT V.;STOLL, DEBORAH, SYNTH. COMMUN., 21,(1991) N, C. 223-227
  作者：HOFFMAN, ROBERT V.、STOLL, DEBORAH

  DOI：——

  日期：——