(Z)-N,N-diisopropyl-3-(trimethylstannyl)-2-heptenamide | 363138-71-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-N,N-diisopropyl-3-(trimethylstannyl)-2-heptenamide
• 英文别名: (Z)-N,N-di(propan-2-yl)-3-trimethylstannylhept-2-enamide
• CAS: 363138-71-0
• 化学式: C₁₆H₃₃NOSn
• 分子量: 374.154
• InChiKey: UFRJHGBLPVTMDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.63
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (Z)-N,N-diisopropyl-3-(trimethylstannyl)-2-heptenamide 在 溶剂黄146 作用下， 生成 N,N-diisopropyl-2-heptenamide
  参考文献：
  名称：

  Carbamoylstannation of Terminal Alkynes with Carbamoylstannanes:  Catalyst-Dependent Regiochemical Reversal

  摘要：

  Rh(acac)(CO)(2) catalyzes addition of (N,N-diisopropylcarbamoyl)trimethylstannane to terminal alkynes to give (Z)-beta-stannyl-alpha,beta-unsaturated amides with terminal attachment of the amide group, while the use of Ni(COd)(2) results in the reversal of the regioselectivity. A mechanism initiated by the oxidative addition of the carbamoylstannane was proposed on the basis of the isolation of (trimethylstannyl)(N,N-diisopropylcarbamoyl)[1,2-bis(dimethylphosphtno)ethane]pallidium.

  DOI：

  10.1021/om000423+
• 作为产物：
  描述：

  trimethyl-N,N-di-isopropylcarbamoylstannane 、 1-己炔 在 tris(triphenylphosphine)ruthenium(II) chloride 作用下， 以0%的产率得到(Z)-N,N-diisopropyl-3-(trimethylstannyl)-2-heptenamide
  参考文献：
  名称：

  Carbamoylstannation of Terminal Alkynes with Carbamoylstannanes:  Catalyst-Dependent Regiochemical Reversal

  摘要：

  Rh(acac)(CO)(2) catalyzes addition of (N,N-diisopropylcarbamoyl)trimethylstannane to terminal alkynes to give (Z)-beta-stannyl-alpha,beta-unsaturated amides with terminal attachment of the amide group, while the use of Ni(COd)(2) results in the reversal of the regioselectivity. A mechanism initiated by the oxidative addition of the carbamoylstannane was proposed on the basis of the isolation of (trimethylstannyl)(N,N-diisopropylcarbamoyl)[1,2-bis(dimethylphosphtno)ethane]pallidium.

  DOI：

  10.1021/om000423+