N,N'-1,4-butylenebis(oleamide) | 268539-45-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N'-1,4-butylenebis(oleamide)
• 英文别名: (Z)-N-[4-[[(Z)-octadec-9-enoyl]amino]butyl]octadec-9-enamide
• CAS: 268539-45-3
• 化学式: C₄₀H₇₆N₂O₂
• 分子量: 617.056
• InChiKey: AEHUDBLWVXPMKW-CLFAGFIQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.5
• 重原子数：
  44
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  油酸 在 吡啶 、 氯化亚砜 作用下， 以 氯仿 为溶剂， 生成 N,N'-1,4-butylenebis(oleamide)
  参考文献：
  名称：

  Fabrication of Microspheres via Solvent Volatization Induced Aggregation of Self-Assembled Nanomicellar Structures and Their Use as a pH-Dependent Drug Release System

  摘要：

  A series of oleamide derivatives, (C18H34NO)(2)(CH2)(n) [n = 2 (1a), 3 (1b), 4 (1c), or 6 (1d); C18H34NO = oleic amide fragment] and (C18H34NO)(CH2)(6)NH2 (2), have been synthesized and their self-assembly is investigated in ethanol/water media. Self-assembly of 1a and 1b in ethanol/water (1/0.1 v/v) solution (5 mg mL(-1)) yields microspheres (MSs) with the average diameter similar to 10 mu m via a gradual temperature reduction and solvent volatilization process. Under the same self-assembly conditions, microrods (average diameter similar to 6 mu m and several tens of micrometers in length), micronecklace-like, and shape-irregular microparticles are formed from the self-assembly of 1 c, id, and 2, respectively. The kinetics of evolution for their self-assemblies by dynamic light scattering technique and in situ observation by optical microscopy reveals that the microstructures formation is from a well-behaved aggregation of nanoscale micelles induced by solvent volatilization. The FT-IR and temperature-dependent H-1-NMR spectra demonstrate the hydrogen bonding force and pi-pi stacking, which drove the self-assembly of all oleamide derivatives in ethanol/water. Among the fabricated microstructures, the MSs from 1a exhibit the best dispersity, which thus have been used as a scaffold for the in vitro release of doxorubicin. The results demonstrate a pH-sensitive release process, enhanced release specifically at low pH 5.2.

  DOI：

  10.1021/la303634y

文献信息

• DEFOAMING AGENT
  申请人：San Nopco Limited

  公开号：EP2392392A1

  公开（公告）日：2011-12-07

  The object of the present invention is to provide a defoaming agent that is superior in defoaming properties (foam-breaking, foam-inhibiting effect, defoaming durability). The present invention is a defoaming agent comprising a fatty acid amide (A), a base oil (B) that is liquid at 25°C, an oil thickening agent (C), and a surfactant (D), wherein the content of the fatty acid amide (A) is 1 to 10% by weight, the content of the base oil (B) that is liquid at 25°C is 71 to 97.9% by weight, the content of the oil thickening agent (C) is 0.1 to 10% by weight, and the content of the surfactant (D) is 1 to 9% by weight based on the weight of the fatty acid amide (A), the base oil (B) that is liquid at 25°C, the oil thickening agent (C), and the surfactant (D), and the viscosity (25°C) at a shear rate of 1000 s-1 is 0.1 to 1.0 Pa•s.

  本发明的目的是提供一种消泡性能（破泡、抑泡效果、消泡持久性）优异的消泡剂。 本发明是一种消泡剂，包括脂肪酸酰胺（A）、25°C 时呈液态的基础油（B）、油稠化剂（C）和表面活性剂（D），其中脂肪酸酰胺（A）的含量为 1 至 10%（重量百分比），25°C 时呈液态的基础油（B）的含量为 71 至 97.9% (重量)，油增稠剂 (C) 的含量为 0.1 至 10% (重量)，表面活性剂 (D) 的含量为 1 至 9% (重量)，以脂肪酸酰胺 (A)、25°C 时为液态的基础油 (B)、油增稠剂 (C) 和表面活性剂 (D) 的重量为基准，剪切速率为 1000 s-1 时的粘度 (25°C) 为 0.1 至 1.0 Pa-s。
• Additive for bioethanol fermentation process and method for producing bioethanol
  申请人：SAN NOPCO LTD.

  公开号：US10125378B2

  公开（公告）日：2018-11-13

  There is provided an additive for a bioethanol fermentation process comprising a polyoxyalkylene compound (A) having a Griffin's HLB value in the range of 0 to 6, a polyoxyalkylene polyol (B) and a base oil (C) that is liquid at 25° C. The compound (A) is preferably a mixture of a compound represented by a general formula (1) and a compound represented by a general formula (2). In the formula, R1 and R3 represent alkyl or alkenyl, R2 and R4 represent a hydrogen atom or a monovalent organic group, AO represents oxyalkylene having a carbon number of 3 to 18, a reaction residue of glycidol, a reaction residue of an alkyl glycidyl ether or a reaction residue of an alkenyl glycidyl ether, EO represents oxyethylene, m and n are 1 to 100, and p is 3 to 10. R1O-(AO)m—R2  (1) R3O-(AO)n-(EO)p—R4  (2)

  本发明提供了一种用于生物乙醇发酵工艺的添加剂，该添加剂包括格里芬 HLB 值在 0 至 6 之间的聚氧亚烷基化合物（A）、聚氧亚烷基多元醇（B）和在 25°C 时为液态的基础油（C）。式中，R1 和 R3 代表烷基或烯基，R2 和 R4 代表氢原子或一价有机基团，AO 代表碳数为 3 至 18 的氧亚烷基、缩水甘油的反应残余物、烷基缩水甘油醚的反应残余物或烯基缩水甘油醚的反应残余物，EO 代表氧乙烯，m 和 n 为 1 至 100，p 为 3 至 10。 R1O-(AO)m-R2 (1) R3O-(AO)n-(EO)p-R4 (2)
• Polycarbonate-based resin composition and molded product thereof
  申请人：IDEMITSU KOSAN CO., LTD.

  公开号：US11161977B2

  公开（公告）日：2021-11-02

  Provided are: a polycarbonate-based resin composition, including a polycarbonate-based resin (A) containing a polycarbonate-polyorganosiloxane copolymer (A1) having a predetermined structure, and 0.1 part by mass or more to 40 parts by mass or less of a white pigment (B) with respect to 100 parts by mass of the polycarbonate-based resin (A), wherein the white pigment (B) has an organic layer on a surface thereof, and a highest peak temperature of an evolved gas analysis curve of the organic layer obtained by evolved gas analysis with a pyrolysis gas chromatograph apparatus and a FID detector is 390° C. or more; and a molded article thereof.

  提供了：一种聚碳酸酯基树脂组合物，包括含有具有预定结构的聚碳酸酯-聚有机硅氧烷共聚物（A1）的聚碳酸酯基树脂（A），以及相对于 100 份聚碳酸酯基树脂（A）质量的 0.1份（质量）或更多至40份（质量）或更少的白色颜料（B）（相对于100份（质量）的聚碳酸酯基树脂（A）），其中白色颜料（B）在其表面具有有机层，并且通过使用热解气相色谱仪装置和FID检测器进行挥发气体分析而获得的有机层的挥发气体分析曲线的最高峰温度为390℃或更高；以及其模塑制品。
• ADDITIVE FOR BIOETHANOL FERMENTATION PROCESS AND METHOD FOR PRODUCING BIOETHANOL
  申请人：SAN NOPCO LTD.

  公开号：US20170349916A1

  公开（公告）日：2017-12-07

  There is provided an additive for a bioethanol fermentation process comprising a polyoxyalkylene compound (A) having a Griffin's HLB value in the range of 0 to 6, a polyoxyalkylene polyol (B) and a base oil (C) that is liquid at 25° C. The compound (A) is preferably a mixture of a compound represented by a general formula (1) and a compound represented by a general formula (2). In the formula, R 1 and R 3 represent alkyl or alkenyl, R 2 and R 4 represent a hydrogen atom or a monovalent organic group, AO represents oxyalkylene having a carbon number of 3 to 18, a reaction residue of glycidol, a reaction residue of an alkyl glycidyl ether or a reaction residue of an alkenyl glycidyl ether, EO represents oxyethylene, m and n are 1 to 100, and p is 3 to 10. R 1 O-(AO) m —R 2 (1) R 3 O-(AO) n -(EO) p —R 4 (2)
• POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED ARTICLE THEREOF
  申请人：IDEMITSU KOSAN CO., LTD.

  公开号：US20180355113A1

  公开（公告）日：2018-12-13

  Provided is a polycarbonate-based resin composition, including a polycarbonate-based resin (A) containing a predetermined polycarbonate-polyorganosiloxane copolymer (A1), and 0.5 part by mass to 40 parts by mass of a white pigment (B) and 0.02 part by mass to 5.0 parts by mass of a hydrolysis resistant agent (C) with respect to 100 parts by mass of the polycarbonate-based resin (A).