3,6-di(1H-indol-2-yl)-9H-carbazole | 1402073-80-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3,6-di(1H-indol-2-yl)-9H-carbazole
• 英文别名: 3,6-di(indol-2-yl)carbazole；3,6-bis(1H-indol-2-yl)-9H-carbazole
• CAS: 1402073-80-6
• 化学式: C₂₈H₁₉N₃
• 分子量: 397.479
• InChiKey: RTCKAFWJDFAZHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  31
• 可旋转键数：
  2
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  47.4
• 氢给体数：
  3
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  3,6-di(1H-indol-2-yl)-9H-carbazole 在 sodium tetrahydroborate 、 三氯氧磷 作用下， 以 乙醇 为溶剂， 反应 12.33h， 生成 8,17,22,31,38-Pentazaoctacyclo[31.3.1.12,6.13,36.07,15.09,14.024,32.025,30]nonatriaconta-1(36),2,4,6(39),7(15),9,11,13,24(32),25,27,29,33(37),34-tetradecaene
  参考文献：
  名称：

  Synthesis of macrocyclic systems derived from di-(2-indolyl)heteroarenes

  摘要：

  A number of new 3,6-di-(2-indolyl)-dibenzofuran and carbazole derivatives have been prepared from dibenzofuran and carbazole linkers via the Fischer indole synthesis. The bis-indoles were successfully formylated at C3 and the resulting dicarbaldehydes were combined with diamines to generate indole based imine macrocyclic systems. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.08.063
• 作为产物：
  描述：

  咔唑 在 aluminum (III) chloride 、 甲烷磺酸 、 溶剂黄146 作用下， 以 二硫化碳 、 乙醇 为溶剂， 反应 9.0h， 生成 3,6-di(1H-indol-2-yl)-9H-carbazole
  参考文献：
  名称：

  Synthesis of macrocyclic systems derived from di-(2-indolyl)heteroarenes

  摘要：

  A number of new 3,6-di-(2-indolyl)-dibenzofuran and carbazole derivatives have been prepared from dibenzofuran and carbazole linkers via the Fischer indole synthesis. The bis-indoles were successfully formylated at C3 and the resulting dicarbaldehydes were combined with diamines to generate indole based imine macrocyclic systems. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.08.063

文献信息

• Some electrophilic reactivity studies of di-(2-indolyl)dibenzofurans and di-(2-indolyl)carbazoles
  作者：Ibrahim F. Sengul、Kittiya Somphol、Hakan Kandemir、Naresh Kumar、David StC. Black

  DOI：10.1016/j.tet.2014.11.014

  日期：2014.12

  3,6-Bis-(2-indolyl)dibenzofurans 1,2, and carbazoles 3-6 underwent a range of electrophilic substitution reactions to produce formyl indoles 7-12, biindolyls 24-28 and 33-34, glyoxylamides 40-42, and amides 48. (C) 2014 Elsevier Ltd. All rights reserved.