2-chloro-N-[diphenoxyphosphoryl-(4-methoxyphenyl)methyl]acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-chloro-N-[diphenoxyphosphoryl-(4-methoxyphenyl)methyl]acetamide
• 化学式: C₂₂H₂₁ClNO₅P
• 分子量: 445.839
• InChiKey: KKSBDIZKWXUTRN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  30
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  73.9
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  selenomorpholine 、 2-chloro-N-[diphenoxyphosphoryl-(4-methoxyphenyl)methyl]acetamide 在 三乙胺 作用下， 以 丙酮 为溶剂， 以76%的产率得到O,O-diphenyl [4-methoxyphenyl-(2-selenomorpholin-4-yl-acetylamino)methyl] phosphonate
  参考文献：
  名称：

  SYNTHESIS OF O,O-DIPHENYL [SUBSTITUTED (2-SELENOMORPHOLIN-4-YL-ACETYL AMINO)] ALKYL PHOSPHONATES

  摘要：

  A series of O,O-diphenyl [substituted (2-selenomorpholin-4-yl-acetyl amino)] alkyl phosphonates were synthesized by the reactions of selenomorpholine with O,O-diphenyl 2-chloro- acetylamino alkyl phosphonates. The structures of all new compounds have been confirmed by H-1 NMR, P-31 NMR, IR spectroscopy, Mass spectroscopy and elemental analyses.

  DOI：

  10.1080/10426500490459687
• 作为产物：
  描述：

  diphenyl <1-amino-2-(4-methoxyphenyl)>ethylphosphonate 、 氯乙酰氯 在 三乙胺 作用下， 以 氯仿 为溶剂， 反应 2.0h， 生成 2-chloro-N-[diphenoxyphosphoryl-(4-methoxyphenyl)methyl]acetamide
  参考文献：
  名称：

  SYNTHESIS OF O,O-DIPHENYL [SUBSTITUTED (2-SELENOMORPHOLIN-4-YL-ACETYL AMINO)] ALKYL PHOSPHONATES

  摘要：

  A series of O,O-diphenyl [substituted (2-selenomorpholin-4-yl-acetyl amino)] alkyl phosphonates were synthesized by the reactions of selenomorpholine with O,O-diphenyl 2-chloro- acetylamino alkyl phosphonates. The structures of all new compounds have been confirmed by H-1 NMR, P-31 NMR, IR spectroscopy, Mass spectroscopy and elemental analyses.

  DOI：

  10.1080/10426500490459687

文献信息

• SYNTHESIS OF O,O-DIPHENYL [SUBSTITUTED (2-SELENOMORPHOLIN-4-YL-ACETYL AMINO)] ALKYL PHOSPHONATES
  作者：Liming Hu、Zhiyuan Chen、Shengmei Lu、Xueshu Li、Zhaojie Liu、Hansheng Xu

  DOI：10.1080/10426500490459687

  日期：2004.6

  A series of O,O-diphenyl [substituted (2-selenomorpholin-4-yl-acetyl amino)] alkyl phosphonates were synthesized by the reactions of selenomorpholine with O,O-diphenyl 2-chloro- acetylamino alkyl phosphonates. The structures of all new compounds have been confirmed by H-1 NMR, P-31 NMR, IR spectroscopy, Mass spectroscopy and elemental analyses.