6-deoxo-castasteron | 87833-54-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 6-deoxo-castasteron
• 英文别名: 6-deoxocastasterone；(2R,3S,5S,8R,9S,10S,13S,14S,17R)-17-[(2S,3R,4R,5S)-3,4-dihydroxy-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-2,3-diol
• CAS: 87833-54-3
• 化学式: C₂₈H₅₀O₄
• 分子量: 450.703
• InChiKey: VXBLCLVRWCLEOX-BFYSZXNBSA-N

物化性质

• 沸点：
  568.1±25.0 °C(Predicted)
• 密度：
  1.083±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  6-deoxoteasterone 在 palladium on activated charcoal 四氢呋喃 、 吡啶 、 氢氧化钾 、 四氧化锇 、 氢气 、 lithium carbonate 、 对甲苯磺酸 、 溶剂黄146 、 N-甲基吗啉氧化物 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 14.0h， 生成 6-deoxo-castasteron
  参考文献：
  名称：

  Takatsuto, Suguru; Watanabe, Tsuyoshi; Fujioka, Shozo, Journal of Chemical Research, Miniprint, 1997, # 4, p. 901 - 924

  摘要：

  DOI：

文献信息

• Synthesis of naturally occurring brassinosteroids employing cleavage of 23,34-epoxides as key reactions. Synthesis of brassinolide, castasterone, dolicholide, dolichosterone, homodolicholide, homodolichosterone, 6-deoxocastasterone and 6-deoxodolichosterone
  作者：Kenji Mori、Masayuki Sakakibara、Katsuhide Okada

  DOI：10.1016/s0040-4020(01)91129-9

  日期：1984.1

  Eight new plant growth-promoting steroids (brassinolide, castasterone, dolicholide, dolichosterone, homodolicholide, homodolichosterone, 6-deoxocastasterone and 6-deoxodolichosterone) were synthesized by the regio- and stereoselective ring-opening reactions of 23,24-epoxides prepared from stigmasterol.

  通过由白豆甾醇制备的23,24-环氧化合物的区域和立体选择性开环反应合成了八种新的促进植物生长的类固醇（油菜素内酯，蓖麻甾酮，三聚乙内酯，三聚二十碳二烯酮，高二羟乙内酯，高聚雌甾烯酮，6-脱氧基castasterone和6-脱氧二烯基甾烷酮）。
• Cytochrome P450 hydroxylase, an important enzyme in brassinosteroid biosynthesis of plants
  申请人：Korea Kumho Petrochemical Co. Ltd.

  公开号：EP1209227A2

  公开（公告）日：2002-05-29

  The present invention provides a nucleic acid molecule encoding a dark-inducible cytochrome P450 hydroxylase that catalyzes the brassinosteroid biosynthesis through C-2 hydroxylations in plants. The invention also describes the methods and processes for generating expression cassettes and plasmids and for the use of these expression cassettes and plasmids to synthesize the cytochrome P450 hydroxylase or biologically active fragments of such an enzyme. The invention can be utilized to improve or decrease the stem growth of transgenic plants containing the nucleic acid molecule so that they exhibit improved growth rate and resistance to environmental stress and to identify other proteins involved in the brassinosteroid biosynthesis and in the plant growth regulation.

  本发明提供了一种编码暗诱导细胞色素P450羟化酶的核酸分子，该酶通过C-2羟化作用催化植物中铜绿素的生物合成。本发明还描述了生成表达盒和质粒以及使用这些表达盒和质粒合成细胞色素 P450 羟化酶或这种酶的生物活性片段的方法和过程。本发明可用于改善或降低含有核酸分子的转基因植物的茎部生长，使其表现出更好的生长速度和对环境胁迫的抵抗力，还可用于鉴定参与铜绿素生物合成和植物生长调节的其他蛋白质。
• GENE CONCERNING BRASSINOSTEROID-SENSITIVITY OF PLANTS AND UTILIZATION THEREOF
  申请人：National Institute of Agrobiological Sciences

  公开号：EP1275719A1

  公开（公告）日：2003-01-15

  The present inventors successfully produced rice dwarf mutant d61 and also isolated the OsBRI1 gene which corresponds to a region in the d61 locus. OsBRI1 is found to increase plant brassinosteroid sensitivity. Moreover, the present inventors showed that OsBRI1 functions in growth and development process of- rice, such as, internode elongation by inducing internode cell elongation and the inclination of the lamina joint. By introducing antisense nucleotides or dominant negative of OsBRI1, the present inventors produced transgenic rice plants whose phenotype was modified.

  本发明人成功培育出水稻矮秆突变体 d61，并分离出与 d61 基因座中一个区域相对应的 OsBRI1 基因。研究发现，OsBRI1 能提高植物对黄铜类固醇的敏感性。此外，本发明人还发现 OsBRI1 在水稻的生长发育过程中起作用，如通过诱导节间细胞伸长和叶片关节倾斜来实现节间伸长。通过引入 OsBRI1 的反义核苷酸或显性阴性，本发明人培育出了表型发生改变的转基因水稻植株。
• Screening method for identifying genes involved in plant cell cycle
  申请人：VIB VZM

  公开号：EP2527451A1

  公开（公告）日：2012-11-28

  The present invention relates to a novel method for screening proteins related to and/or involved in plant cell cycle. It further relates to proteins isolated with the method, and the use of those proteins, and/or the genes encoding those proteins for modulating plant yield and plant growth.

  本发明涉及一种筛选与植物细胞周期有关和/或参与植物细胞周期的蛋白质的新方法。本发明还涉及用该方法分离的蛋白质，以及使用这些蛋白质和/或编码这些蛋白质的基因来调节植物产量和植物生长。
• Production of cotton fiber with improved fiber characteristics
  申请人：——

  公开号：US20010018773A1

  公开（公告）日：2001-08-30

  Methods are disclosed to achieve an improvement in the characteristics and yield of cotton fibers. In one method, a cotton plant of the genus Gossypium in seed form or in growth stage is treated with a brassinosteroid. In another method, an ovule culture is prepared from a cotton plant of the genus Gossypium in a brassinosteroid-containing liquid medium. Cotton fibers with improved fiber characteristics are obtained from the cotton bolls of the treated plant or from the cultured ovules. Also disclosed are a method for inducing specific genes expression in a cotton plant to produce cotton fibers with improved fiber characteristics by treatment with a brassinosteroid, and a cotton plant produced by this method; as well as a novel gene capable of changing the degree of its expression found in the ovules of a cotton plant treated with a brassinosteroid, a gene capable of hybridizing with this novel gene, a recombinant plasmid containing this novel gene, a transformant containing this recombinant plasmid, and the like.

  已公开的方法可改善棉纤维的特性和产量。在一种方法中，用黄铜类固醇处理处于种子状态或生长阶段的棉属植物。另一种方法是在含黄铜类固醇的液体培养基中制备棉属植物的胚珠培养物。从经过处理的棉花植株的棉铃或培养的胚珠中获得纤维特性得到改善的棉纤维。本发明还公开了一种诱导特定基因在棉花植株中表达的方法，该方法通过使用类黄铜激素处理棉花植株，从而生产出具有改良纤维特性的棉纤维；还公开了一种能够改变其在使用类黄铜激素处理的棉花植株胚珠中表达程度的新型基因、一种能够与该新型基因杂交的基因、一种含有该新型基因的重组质粒、一种含有该重组质粒的转化体等。