methyl 2,4-di-O-methyl-L-rhamnopyranoside | 109008-08-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 2,4-di-O-methyl-L-rhamnopyranoside
• 英文别名: methyl 2,4-di-O-methyl-rhamnopyranoside；(3R,4R,5R,6S)-2,3,5-trimethoxy-6-methyloxan-4-ol
• CAS: 109008-08-4
• 化学式: C₉H₁₈O₅
• 分子量: 206.239
• InChiKey: MPOCYDUAXAJLOT-WUQSDXJHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  在 盐酸 、 silver carbonate 作用下， 反应 2.0h， 生成 methyl-2,3,4,6-tetra-O-methyl-D-glucopyranoside 、 ruscogenin 1-O-methyl ether 、 methyl 2,4-di-O-methyl-L-rhamnopyranoside
  参考文献：
  名称：

  Watanabe, Yoshiaki; Sanada, Shuichi; Ida, Yoshiteru, Chemical and pharmaceutical bulletin, 1983, vol. 31, # 6, p. 1980 - 1990

  摘要：

  DOI：

文献信息

• Studies on the constituents of Clematis species. IV. On the saponins of the root of Clematis chinensis Osbeck. IV.
  作者：HARUHISA KIZU、TSUYOSHI TOMIMORI

  DOI：10.1248/cpb.30.859

  日期：——

  Four triterpenoid prosapogenins named CP7a, CP8a, CP9a and CP10a have been isolated from the alkaline hydrolysate of the crude saponin obtained from the root of Clematis chinensis OSBECK. On the basis of chemical and physicochemical evidence, they were characterized as follows : CP7a (I), oleanolic acid 3-O-β-D-glucopyranosyl-(1→4)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside ; CP8a (VI), hederagenin 3-O-β-D-glucopyranosyl-(1→4)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside ; CP9a (XI), oleanolic acid 3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→4)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside ; CP10a (XIII), hederagenin 3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→4)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside.

  从以威灵仙根部的粗皂苷经过碱性水解后的水解产物中，分离得到了4个三萜皂苷元，分别命名为CP7a、CP8a、CP9a和CP10a。基于化学和物理化学证据，它们被鉴定如下：CP7a（I）为齐墩果酸3-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃木糖基-(1→3)-α-L-吡喃鼠李糖基-(1→2)-α-L-吡喃阿拉伯糖苷；CP8a（VI）为常春藤苷元3-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃木糖基-(1→3)-α-L-吡喃鼠李糖基-(1→2)-α-L-吡喃阿拉伯糖苷；CP9a（XI）为齐墩果酸3-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃木糖基-(1→3)-α-L-吡喃鼠李糖基-(1→2)-α-L-吡喃阿拉伯糖苷；CP10a（XIII）为常春藤苷元3-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃木糖基-(1→3)-α-L-吡喃鼠李糖基-(1→2)-α-L-吡喃阿拉伯糖苷。
• Kimata, Hiroko; Nakashima, Taeko; Kokubin, Setsuko, Chemical and pharmaceutical bulletin, 1983, vol. 31, # 6, p. 1998 - 2005
  作者：Kimata, Hiroko、Nakashima, Taeko、Kokubin, Setsuko、Nakayama, Keiso、Mitoma, Yohko,、et al.

  DOI：——

  日期：——